Associations between Mediterranean Diet Adherence, Quality of Life, and Mental Health in Patients with Multiple Sclerosis: A Cross-Sectional Study
The Mediterranean diet (MD) is well-known as a diet which may exert a protective effect against neurodegenerative diseases, including multiple sclerosis (MS). To date, only a few clinical surveys have assessed the potential effects of the MD in patients with MS. The purpose of the present study is t...
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creator | Dakanalis, Antonios Tryfonos, Christina Pavlidou, Eleni Vadikolias, Konstantinos Papadopoulou, Sousana K Alexatou, Olga Vorvolakos, Theofanis Chrysafi, Maria Fotiou, Dimitrios Mentzelou, Maria Serdari, Aspasia Chatzidimitriou, Maria Dimoliani, Sophia Tsourouflis, Gerasimos Giaginis, Constantinos |
description | The Mediterranean diet (MD) is well-known as a diet which may exert a protective effect against neurodegenerative diseases, including multiple sclerosis (MS). To date, only a few clinical surveys have assessed the potential effects of the MD in patients with MS. The purpose of the present study is to evaluate the potential effects of MD compliance on disease disability, quality of life, physical activity, depressive symptomatology, and blood biochemical parameters related to nutritional status in MS patients, considering several socio-demographic, anthropometric, and lifestyle characteristics.
This is a cross-sectional study conducted on 558 adults with MS aged 18-64 years. Relevant questionnaires were utilized to evaluate socio-demographic and anthropometric parameters, disease disability (Expanded Disability Status Scale, EDSS), multidimensional health-related quality (MS Quality of Life-54, MSQOL-54), physical activity levels (International Physical Activity Questionnaire, IPAQ), depression (Beck Depression Inventory II, BDI-II), and MD adherence (MedDietScore), while several blood biochemical parameters were retrieved from the patients' medical records.
Enhanced MD compliance was independently associated with a decreased frequency of overweight/obesity, as well as abdominal obesity, in patients suffering from MS. Elevated MD compliance was also independently associated with a decreased incidence of advanced disease disability, a higher prevalence of elevated physical activity, an improved quality of life, and lower depressive symptoms, as well as higher levels of certain blood biochemical parameters, which are effective indicators of iron deficiency and malnutrition.
The present study found that higher MD adherence may slow down disease disability, promoting a better quality of life and mental health in adults with MS. Future prospective surveys are required to obtain conclusive results. |
doi_str_mv | 10.3390/jpm14020199 |
format | Article |
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This is a cross-sectional study conducted on 558 adults with MS aged 18-64 years. Relevant questionnaires were utilized to evaluate socio-demographic and anthropometric parameters, disease disability (Expanded Disability Status Scale, EDSS), multidimensional health-related quality (MS Quality of Life-54, MSQOL-54), physical activity levels (International Physical Activity Questionnaire, IPAQ), depression (Beck Depression Inventory II, BDI-II), and MD adherence (MedDietScore), while several blood biochemical parameters were retrieved from the patients' medical records.
Enhanced MD compliance was independently associated with a decreased frequency of overweight/obesity, as well as abdominal obesity, in patients suffering from MS. Elevated MD compliance was also independently associated with a decreased incidence of advanced disease disability, a higher prevalence of elevated physical activity, an improved quality of life, and lower depressive symptoms, as well as higher levels of certain blood biochemical parameters, which are effective indicators of iron deficiency and malnutrition.
The present study found that higher MD adherence may slow down disease disability, promoting a better quality of life and mental health in adults with MS. Future prospective surveys are required to obtain conclusive results.</description><identifier>ISSN: 2075-4426</identifier><identifier>EISSN: 2075-4426</identifier><identifier>DOI: 10.3390/jpm14020199</identifier><identifier>PMID: 38392632</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Adults ; Blood ; Care and treatment ; Chronic illnesses ; Cross-sectional studies ; Demography ; Diet ; Disease ; Epstein-Barr virus ; Exercise ; Fish oils ; Iron deficiency ; Life expectancy ; Lifestyles ; Malnutrition ; Medical records ; Mental depression ; Mental disorders ; Mental health ; Multiple sclerosis ; Neurodegenerative diseases ; Nutrient deficiency ; Nutrition research ; Nutritional status ; Obesity ; Patient compliance ; Patients ; Physical activity ; Quality of life ; Risk factors ; Seafood ; Surveys</subject><ispartof>Journal of personalized medicine, 2024-02, Vol.14 (2), p.199</ispartof><rights>COPYRIGHT 2024 MDPI AG</rights><rights>2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c346t-c8b7d64610f45948482a8e8058587685ddf63e3a43a5a10853832aa268fafad83</cites><orcidid>0000-0002-7764-3544 ; 0000-0002-2101-4546 ; 0000-0003-2878-4831 ; 0000-0002-2328-3862</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38392632$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dakanalis, Antonios</creatorcontrib><creatorcontrib>Tryfonos, Christina</creatorcontrib><creatorcontrib>Pavlidou, Eleni</creatorcontrib><creatorcontrib>Vadikolias, Konstantinos</creatorcontrib><creatorcontrib>Papadopoulou, Sousana K</creatorcontrib><creatorcontrib>Alexatou, Olga</creatorcontrib><creatorcontrib>Vorvolakos, Theofanis</creatorcontrib><creatorcontrib>Chrysafi, Maria</creatorcontrib><creatorcontrib>Fotiou, Dimitrios</creatorcontrib><creatorcontrib>Mentzelou, Maria</creatorcontrib><creatorcontrib>Serdari, Aspasia</creatorcontrib><creatorcontrib>Chatzidimitriou, Maria</creatorcontrib><creatorcontrib>Dimoliani, Sophia</creatorcontrib><creatorcontrib>Tsourouflis, Gerasimos</creatorcontrib><creatorcontrib>Giaginis, Constantinos</creatorcontrib><title>Associations between Mediterranean Diet Adherence, Quality of Life, and Mental Health in Patients with Multiple Sclerosis: A Cross-Sectional Study</title><title>Journal of personalized medicine</title><addtitle>J Pers Med</addtitle><description>The Mediterranean diet (MD) is well-known as a diet which may exert a protective effect against neurodegenerative diseases, including multiple sclerosis (MS). To date, only a few clinical surveys have assessed the potential effects of the MD in patients with MS. The purpose of the present study is to evaluate the potential effects of MD compliance on disease disability, quality of life, physical activity, depressive symptomatology, and blood biochemical parameters related to nutritional status in MS patients, considering several socio-demographic, anthropometric, and lifestyle characteristics.
This is a cross-sectional study conducted on 558 adults with MS aged 18-64 years. Relevant questionnaires were utilized to evaluate socio-demographic and anthropometric parameters, disease disability (Expanded Disability Status Scale, EDSS), multidimensional health-related quality (MS Quality of Life-54, MSQOL-54), physical activity levels (International Physical Activity Questionnaire, IPAQ), depression (Beck Depression Inventory II, BDI-II), and MD adherence (MedDietScore), while several blood biochemical parameters were retrieved from the patients' medical records.
Enhanced MD compliance was independently associated with a decreased frequency of overweight/obesity, as well as abdominal obesity, in patients suffering from MS. Elevated MD compliance was also independently associated with a decreased incidence of advanced disease disability, a higher prevalence of elevated physical activity, an improved quality of life, and lower depressive symptoms, as well as higher levels of certain blood biochemical parameters, which are effective indicators of iron deficiency and malnutrition.
The present study found that higher MD adherence may slow down disease disability, promoting a better quality of life and mental health in adults with MS. Future prospective surveys are required to obtain conclusive results.</description><subject>Adults</subject><subject>Blood</subject><subject>Care and treatment</subject><subject>Chronic illnesses</subject><subject>Cross-sectional studies</subject><subject>Demography</subject><subject>Diet</subject><subject>Disease</subject><subject>Epstein-Barr virus</subject><subject>Exercise</subject><subject>Fish oils</subject><subject>Iron deficiency</subject><subject>Life expectancy</subject><subject>Lifestyles</subject><subject>Malnutrition</subject><subject>Medical records</subject><subject>Mental depression</subject><subject>Mental disorders</subject><subject>Mental health</subject><subject>Multiple sclerosis</subject><subject>Neurodegenerative diseases</subject><subject>Nutrient deficiency</subject><subject>Nutrition research</subject><subject>Nutritional status</subject><subject>Obesity</subject><subject>Patient compliance</subject><subject>Patients</subject><subject>Physical activity</subject><subject>Quality of life</subject><subject>Risk factors</subject><subject>Seafood</subject><subject>Surveys</subject><issn>2075-4426</issn><issn>2075-4426</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNptUU1v1DAQtRCIVqUn7sgSR0hxbMdxuEVboEhbAVo4R7P2mHqVOIvtqNq_wS_GqxYoEp6DR0_vzdcj5HnNLoTo2Jvdfqol46zuukfklLO2qaTk6vGD_IScp7Rj5emGc8WekhOhRceV4KfkZ5_SbDxkP4dEt5hvEQO9RuszxggBIdBLj5n29gYjBoOv6ZcFRp8PdHZ07V0BINgiCRlGeoUw5hvqA_1cahYs0VtfgOtlzH4_It2YEeOcfHpLe7oqWao2aI7ti3qTF3t4Rp44GBOe3_9n5Nv7d19XV9X604ePq35dGSFVrozetlZJVTMnm05qqTlo1KzRjW6Vbqx1SqAAKaCBuuxeluYAXGkHDqwWZ-TlXd19nH8smPKwm5dYxkgD7wTrGs469Zf1HUYcfHBzjmAmn8zQt1oyWaumLayL_7BKWJy8mQM6X_B_BK_uBOZ4gohu2Ec_QTwMNRuOzg4PnC3sF_ejLtsJ7R_ubx_FLzRenM4</recordid><startdate>20240201</startdate><enddate>20240201</enddate><creator>Dakanalis, Antonios</creator><creator>Tryfonos, Christina</creator><creator>Pavlidou, Eleni</creator><creator>Vadikolias, Konstantinos</creator><creator>Papadopoulou, Sousana K</creator><creator>Alexatou, Olga</creator><creator>Vorvolakos, Theofanis</creator><creator>Chrysafi, Maria</creator><creator>Fotiou, Dimitrios</creator><creator>Mentzelou, Maria</creator><creator>Serdari, Aspasia</creator><creator>Chatzidimitriou, Maria</creator><creator>Dimoliani, Sophia</creator><creator>Tsourouflis, Gerasimos</creator><creator>Giaginis, Constantinos</creator><general>MDPI AG</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FE</scope><scope>8FH</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>LK8</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><orcidid>https://orcid.org/0000-0002-7764-3544</orcidid><orcidid>https://orcid.org/0000-0002-2101-4546</orcidid><orcidid>https://orcid.org/0000-0003-2878-4831</orcidid><orcidid>https://orcid.org/0000-0002-2328-3862</orcidid></search><sort><creationdate>20240201</creationdate><title>Associations between Mediterranean Diet Adherence, Quality of Life, and Mental Health in Patients with Multiple Sclerosis: A Cross-Sectional Study</title><author>Dakanalis, Antonios ; 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To date, only a few clinical surveys have assessed the potential effects of the MD in patients with MS. The purpose of the present study is to evaluate the potential effects of MD compliance on disease disability, quality of life, physical activity, depressive symptomatology, and blood biochemical parameters related to nutritional status in MS patients, considering several socio-demographic, anthropometric, and lifestyle characteristics.
This is a cross-sectional study conducted on 558 adults with MS aged 18-64 years. Relevant questionnaires were utilized to evaluate socio-demographic and anthropometric parameters, disease disability (Expanded Disability Status Scale, EDSS), multidimensional health-related quality (MS Quality of Life-54, MSQOL-54), physical activity levels (International Physical Activity Questionnaire, IPAQ), depression (Beck Depression Inventory II, BDI-II), and MD adherence (MedDietScore), while several blood biochemical parameters were retrieved from the patients' medical records.
Enhanced MD compliance was independently associated with a decreased frequency of overweight/obesity, as well as abdominal obesity, in patients suffering from MS. Elevated MD compliance was also independently associated with a decreased incidence of advanced disease disability, a higher prevalence of elevated physical activity, an improved quality of life, and lower depressive symptoms, as well as higher levels of certain blood biochemical parameters, which are effective indicators of iron deficiency and malnutrition.
The present study found that higher MD adherence may slow down disease disability, promoting a better quality of life and mental health in adults with MS. Future prospective surveys are required to obtain conclusive results.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>38392632</pmid><doi>10.3390/jpm14020199</doi><orcidid>https://orcid.org/0000-0002-7764-3544</orcidid><orcidid>https://orcid.org/0000-0002-2101-4546</orcidid><orcidid>https://orcid.org/0000-0003-2878-4831</orcidid><orcidid>https://orcid.org/0000-0002-2328-3862</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Adults Blood Care and treatment Chronic illnesses Cross-sectional studies Demography Diet Disease Epstein-Barr virus Exercise Fish oils Iron deficiency Life expectancy Lifestyles Malnutrition Medical records Mental depression Mental disorders Mental health Multiple sclerosis Neurodegenerative diseases Nutrient deficiency Nutrition research Nutritional status Obesity Patient compliance Patients Physical activity Quality of life Risk factors Seafood Surveys |
title | Associations between Mediterranean Diet Adherence, Quality of Life, and Mental Health in Patients with Multiple Sclerosis: A Cross-Sectional Study |
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