Thymic stromal lymphopoietin suppresses markers of neuroinflammation and the JAK2/STAT5 pathway in activated microglia

Thymic stromal lymphopoietin (TSLP) is highly expressed in the central nervous system in response to inflammation, but its exact function remains unclear. In this study, we used a model of LPS-stimulated microglia to investigate the direct impact of TSLP on microglial activation and the underlying m...

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Veröffentlicht in:	European cytokine network (Montrouge) 2023-12, Vol.34 (3), p.21-27
Hauptverfasser:	Zhou, Qiao, Cui, Nanxue, Zhang, Shihai, Zhou, Miaomiao, Xu, Younian
Format:	Artikel
Sprache:	eng
Schlagworte:	Central nervous system Inflammation Janus kinase 2 Lipopolysaccharides Macrophages Microglia Nervous system Oxidative stress Stat5 protein Thymic stromal lymphopoietin Thymus
Online-Zugang:	Volltext
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