Micronization of Levofloxacin Hemihydrate Using Supercritical Trifluoromethane

Micronization of the pharmaceutical substance levofloxacin hemihydrate (LFC) was studied by the RESS method with trifluoromethane (CHF 3 ) as a polar supercritical solvent. Scanning electron microscopy showed that, at a CHF 3 temperature of 50°C, particles of micronized LFC have the shape of microgr...

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Veröffentlicht in:	Russian journal of physical chemistry. B 2023-12, Vol.17 (8), p.1555-1560
Hauptverfasser:	Antonov, E. N., Ivanova, A. G., Krotova, L. I., Mishakov, G. V., Popov, V. K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics Chemistry Chemistry and Materials Science Physical Chemistry Trifluoromethane X ray powder diffraction
Online-Zugang:	Volltext
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