Digestion of lipid micelles leads to increased membrane permeability

Lipid-based drug carriers are an attractive option to solubilise poorly water soluble therapeutics. Previously, we reported that the digestion of a short tail PC lipid (2C6PC) by the PLA2 enzyme has a significant effect on the structure and stability of the micelles it forms. Here, we studied the in...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Nanoscale 2024-02, Vol.16 (5), p.2642-2653
Hauptverfasser:	Xie, Jun, Pink, Demi L, Jayne Lawrence, M, Lorenz, Christian D
Format:	Artikel
Sprache:	eng
Schlagworte:	Composition Digestion Drug carriers Inserts Lipids Membranes Micelles Permeability Structural stability
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!