Dynamic Exchange in 3D Cell Culture Hydrogels Based on Crosslinking of Cyclic Thiosulfinates

Dynamic polymer materials are highly valued substrates for 3D cell culture due to their viscoelasticity, a time‐dependent mechanical property that can be tuned to resemble the energy dissipation of native tissues. Herein, we report the coupling of a cyclic thiosulfinate, mono‐S‐oxo‐4‐methyl asparagu...

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Veröffentlicht in:	Angewandte Chemie 2024-02, Vol.136 (6), p.n/a
Hauptverfasser:	Janssen, Merel L., Liu, Tingxian, Özel, Mertcan, Bril, Maaike, Prasad Thelu, Hari Veera, E. Kieltyka, Roxanne
Format:	Artikel
Sprache:	eng
Schlagworte:	3D Cell Culture Cardiomyocytes Cell culture Crosslinking Cyclic Thiosulfinate Dynamic Covalent Hydrogels Elongation Energy dissipation Hydrogels Mechanical properties Pluripotency Polymers Ring opening Stem cells Stress Relaxation Substrates Thiol-Disulfide Exchange Viscoelastic fluids Viscoelasticity
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