A study of the in-vitro bioactivity, dissolution and antibacterial activity of larnite prepared by a novel sol–gel combustion method using sucrose as a fuel
This article presents the preparation and antibacterial activity of larnite bioceramics, an active calcium silicate ceramic material having the molecular formula Ca 2 SiO 4 . A stepwise sol–gel combustion approach was used to prepare the single phasic larnite. The synthesis of larnite was carried ou...
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| Veröffentlicht in: | Bulletin of materials science 2020-12, Vol.43 (1), p.237, Article 237 |
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| creator | MARY, M CHRISTE SONIA CHATTERJEE, ANKITA ABRAHAM, JAYANTHI SASIKUMAR, S |
| description | This article presents the preparation and antibacterial activity of larnite bioceramics, an active calcium silicate ceramic material having the molecular formula Ca
2
SiO
4
. A stepwise sol–gel combustion approach was used to prepare the single phasic larnite. The synthesis of larnite was carried out with calcium nitrate tetrahydrate as a source of calcium which acts as an oxidizing agent and tetraethyl orthosilicate as a source of silicate which acts as a reducing agent (fuel). The powders thus prepared were calcined at temperatures ranging from 400 to 800°C. X-ray diffraction analysis was used to study the phase formation and determine the hydroxyapatite (HAP) formation during the bioactivity studies. The synthesized materials were also characterized by Fourier-transform infrared, scanning electron microscopy and energy dispersive X-ray techniques. Elemental ionic concentration of the Ca, P and Si in stimulated body fluid (SBF) solution was analysed by inductively coupled plasma-optical emission spectroscopy. The bone-like apatite formation ability of larnite scaffolds was investigated by immersing it in SBF. It was observed that larnite has the capability to deposit HAP within the early stage of immersion. The antimicrobial activity of the larnite was screened against nine clinical pathogens. The fabricated larnite compound was tested against both Gram-positive bacteria (
Staphylococcus aureus
and
Enterococcus
sp.) and Gram-negative bacteria (
Escherichia coli
,
Pseudomonas aeruginosa
,
Serratia marcescens
,
Shigella
sp.,
Proteus mirabilis
,
Salmonella
sp. and
Klebsiella pneumoniae
)
via
the agar diffusion method. The obtained results suggested that the prepared larnite has a high antibacterial property against Gram-negative bacteria because of its thin peptidoglycan layer. From the overall results it is concluded that larnite could be a promising candidate for biomedical applications. |
| doi_str_mv | 10.1007/s12034-020-02208-1 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2920220131</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2920220131</sourcerecordid><originalsourceid>FETCH-LOGICAL-c356t-d9be86053860715ee3c7c13d055f73080a331177a33049884ab2a98a702b72623</originalsourceid><addsrcrecordid>eNp9kc1OxCAUhYnRxHH0BVyRuLV6gba0y8nEv2QSN7omtKUzTDqlAp2kO9_BvQ_nk0inGncuLvcSzvkgHIQuCdwQAH7rCAUWR0AhFIUsIkdoBjlnEU_T_DjMNIEo5sBP0ZlzWwCSxzGZoc8Fdr6vBmxq7DcK6zbaa28NLrSRpddhM1zjSjtnmt5r02LZVqG8LsKxslo2-Fc3MhppW-0V7qzqpFUVLgYscWv2qsEB8fX-sQ5TaXZF7w64nfIbU-He6XaNXV9a4xSWLpjqXjXn6KSWjVMXP32OXu_vXpaP0er54Wm5WEUlS1IfVXmhshQSFhZOEqVYyUvCKkiSmjPIQDJGCOehQZxnWSwLKvNMcqAFpyllc3Q1cTtr3nrlvNia3rbhSkFzOn4pYSSo6KQaX-msqkVn9U7aQRAQYw5iykGEHMQhBzGa2GRyQdyulf1D_-P6BvgzjVo</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2920220131</pqid></control><display><type>article</type><title>A study of the in-vitro bioactivity, dissolution and antibacterial activity of larnite prepared by a novel sol–gel combustion method using sucrose as a fuel</title><source>Indian Academy of Sciences</source><source>SpringerLink Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>Free Full-Text Journals in Chemistry</source><source>ProQuest Central</source><creator>MARY, M CHRISTE SONIA ; CHATTERJEE, ANKITA ; ABRAHAM, JAYANTHI ; SASIKUMAR, S</creator><creatorcontrib>MARY, M CHRISTE SONIA ; CHATTERJEE, ANKITA ; ABRAHAM, JAYANTHI ; SASIKUMAR, S</creatorcontrib><description>This article presents the preparation and antibacterial activity of larnite bioceramics, an active calcium silicate ceramic material having the molecular formula Ca
2
SiO
4
. A stepwise sol–gel combustion approach was used to prepare the single phasic larnite. The synthesis of larnite was carried out with calcium nitrate tetrahydrate as a source of calcium which acts as an oxidizing agent and tetraethyl orthosilicate as a source of silicate which acts as a reducing agent (fuel). The powders thus prepared were calcined at temperatures ranging from 400 to 800°C. X-ray diffraction analysis was used to study the phase formation and determine the hydroxyapatite (HAP) formation during the bioactivity studies. The synthesized materials were also characterized by Fourier-transform infrared, scanning electron microscopy and energy dispersive X-ray techniques. Elemental ionic concentration of the Ca, P and Si in stimulated body fluid (SBF) solution was analysed by inductively coupled plasma-optical emission spectroscopy. The bone-like apatite formation ability of larnite scaffolds was investigated by immersing it in SBF. It was observed that larnite has the capability to deposit HAP within the early stage of immersion. The antimicrobial activity of the larnite was screened against nine clinical pathogens. The fabricated larnite compound was tested against both Gram-positive bacteria (
Staphylococcus aureus
and
Enterococcus
sp.) and Gram-negative bacteria (
Escherichia coli
,
Pseudomonas aeruginosa
,
Serratia marcescens
,
Shigella
sp.,
Proteus mirabilis
,
Salmonella
sp. and
Klebsiella pneumoniae
)
via
the agar diffusion method. The obtained results suggested that the prepared larnite has a high antibacterial property against Gram-negative bacteria because of its thin peptidoglycan layer. From the overall results it is concluded that larnite could be a promising candidate for biomedical applications.</description><identifier>ISSN: 0250-4707</identifier><identifier>EISSN: 0973-7669</identifier><identifier>DOI: 10.1007/s12034-020-02208-1</identifier><language>eng</language><publisher>Bangalore: Indian Academy of Sciences</publisher><subject>Apatite ; Bacterial infections ; Bioceramics ; Biological activity ; Biomedical materials ; Body fluids ; Calcium nitrate ; Chemistry and Materials Science ; Chloride ; Coliforms ; Combustion ; Decomposition ; Dicalcium silicate ; Drug resistance ; E coli ; Emission analysis ; Engineering ; Fourier transforms ; Fractures ; Fuels ; Hydroxyapatite ; Inductively coupled plasma ; Klebsiella ; Materials Science ; Nitrates ; Optical emission spectroscopy ; Oxidizing agents ; Pathogens ; Potassium ; Reducing agents ; Scanning electron microscopy ; Silica ; Silicon ; Sol-gel processes ; Spectrum analysis ; Sucrose ; Tetraethyl orthosilicate ; Transplants & implants</subject><ispartof>Bulletin of materials science, 2020-12, Vol.43 (1), p.237, Article 237</ispartof><rights>Indian Academy of Sciences 2020</rights><rights>Indian Academy of Sciences 2020.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c356t-d9be86053860715ee3c7c13d055f73080a331177a33049884ab2a98a702b72623</citedby><cites>FETCH-LOGICAL-c356t-d9be86053860715ee3c7c13d055f73080a331177a33049884ab2a98a702b72623</cites><orcidid>0000-0003-2533-4923</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2920220131/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2920220131?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,776,780,21367,27901,27902,33721,41464,42533,43781,51294,74045</link.rule.ids></links><search><creatorcontrib>MARY, M CHRISTE SONIA</creatorcontrib><creatorcontrib>CHATTERJEE, ANKITA</creatorcontrib><creatorcontrib>ABRAHAM, JAYANTHI</creatorcontrib><creatorcontrib>SASIKUMAR, S</creatorcontrib><title>A study of the in-vitro bioactivity, dissolution and antibacterial activity of larnite prepared by a novel sol–gel combustion method using sucrose as a fuel</title><title>Bulletin of materials science</title><addtitle>Bull Mater Sci</addtitle><description>This article presents the preparation and antibacterial activity of larnite bioceramics, an active calcium silicate ceramic material having the molecular formula Ca
2
SiO
4
. A stepwise sol–gel combustion approach was used to prepare the single phasic larnite. The synthesis of larnite was carried out with calcium nitrate tetrahydrate as a source of calcium which acts as an oxidizing agent and tetraethyl orthosilicate as a source of silicate which acts as a reducing agent (fuel). The powders thus prepared were calcined at temperatures ranging from 400 to 800°C. X-ray diffraction analysis was used to study the phase formation and determine the hydroxyapatite (HAP) formation during the bioactivity studies. The synthesized materials were also characterized by Fourier-transform infrared, scanning electron microscopy and energy dispersive X-ray techniques. Elemental ionic concentration of the Ca, P and Si in stimulated body fluid (SBF) solution was analysed by inductively coupled plasma-optical emission spectroscopy. The bone-like apatite formation ability of larnite scaffolds was investigated by immersing it in SBF. It was observed that larnite has the capability to deposit HAP within the early stage of immersion. The antimicrobial activity of the larnite was screened against nine clinical pathogens. The fabricated larnite compound was tested against both Gram-positive bacteria (
Staphylococcus aureus
and
Enterococcus
sp.) and Gram-negative bacteria (
Escherichia coli
,
Pseudomonas aeruginosa
,
Serratia marcescens
,
Shigella
sp.,
Proteus mirabilis
,
Salmonella
sp. and
Klebsiella pneumoniae
)
via
the agar diffusion method. The obtained results suggested that the prepared larnite has a high antibacterial property against Gram-negative bacteria because of its thin peptidoglycan layer. From the overall results it is concluded that larnite could be a promising candidate for biomedical applications.</description><subject>Apatite</subject><subject>Bacterial infections</subject><subject>Bioceramics</subject><subject>Biological activity</subject><subject>Biomedical materials</subject><subject>Body fluids</subject><subject>Calcium nitrate</subject><subject>Chemistry and Materials Science</subject><subject>Chloride</subject><subject>Coliforms</subject><subject>Combustion</subject><subject>Decomposition</subject><subject>Dicalcium silicate</subject><subject>Drug resistance</subject><subject>E coli</subject><subject>Emission analysis</subject><subject>Engineering</subject><subject>Fourier transforms</subject><subject>Fractures</subject><subject>Fuels</subject><subject>Hydroxyapatite</subject><subject>Inductively coupled plasma</subject><subject>Klebsiella</subject><subject>Materials Science</subject><subject>Nitrates</subject><subject>Optical emission spectroscopy</subject><subject>Oxidizing agents</subject><subject>Pathogens</subject><subject>Potassium</subject><subject>Reducing agents</subject><subject>Scanning electron microscopy</subject><subject>Silica</subject><subject>Silicon</subject><subject>Sol-gel processes</subject><subject>Spectrum analysis</subject><subject>Sucrose</subject><subject>Tetraethyl orthosilicate</subject><subject>Transplants & implants</subject><issn>0250-4707</issn><issn>0973-7669</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNp9kc1OxCAUhYnRxHH0BVyRuLV6gba0y8nEv2QSN7omtKUzTDqlAp2kO9_BvQ_nk0inGncuLvcSzvkgHIQuCdwQAH7rCAUWR0AhFIUsIkdoBjlnEU_T_DjMNIEo5sBP0ZlzWwCSxzGZoc8Fdr6vBmxq7DcK6zbaa28NLrSRpddhM1zjSjtnmt5r02LZVqG8LsKxslo2-Fc3MhppW-0V7qzqpFUVLgYscWv2qsEB8fX-sQ5TaXZF7w64nfIbU-He6XaNXV9a4xSWLpjqXjXn6KSWjVMXP32OXu_vXpaP0er54Wm5WEUlS1IfVXmhshQSFhZOEqVYyUvCKkiSmjPIQDJGCOehQZxnWSwLKvNMcqAFpyllc3Q1cTtr3nrlvNia3rbhSkFzOn4pYSSo6KQaX-msqkVn9U7aQRAQYw5iykGEHMQhBzGa2GRyQdyulf1D_-P6BvgzjVo</recordid><startdate>20201201</startdate><enddate>20201201</enddate><creator>MARY, M CHRISTE SONIA</creator><creator>CHATTERJEE, ANKITA</creator><creator>ABRAHAM, JAYANTHI</creator><creator>SASIKUMAR, S</creator><general>Indian Academy of Sciences</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>8BQ</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>ABJCF</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>HCIFZ</scope><scope>JG9</scope><scope>KB.</scope><scope>PDBOC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><orcidid>https://orcid.org/0000-0003-2533-4923</orcidid></search><sort><creationdate>20201201</creationdate><title>A study of the in-vitro bioactivity, dissolution and antibacterial activity of larnite prepared by a novel sol–gel combustion method using sucrose as a fuel</title><author>MARY, M CHRISTE SONIA ; CHATTERJEE, ANKITA ; ABRAHAM, JAYANTHI ; SASIKUMAR, S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c356t-d9be86053860715ee3c7c13d055f73080a331177a33049884ab2a98a702b72623</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Apatite</topic><topic>Bacterial infections</topic><topic>Bioceramics</topic><topic>Biological activity</topic><topic>Biomedical materials</topic><topic>Body fluids</topic><topic>Calcium nitrate</topic><topic>Chemistry and Materials Science</topic><topic>Chloride</topic><topic>Coliforms</topic><topic>Combustion</topic><topic>Decomposition</topic><topic>Dicalcium silicate</topic><topic>Drug resistance</topic><topic>E coli</topic><topic>Emission analysis</topic><topic>Engineering</topic><topic>Fourier transforms</topic><topic>Fractures</topic><topic>Fuels</topic><topic>Hydroxyapatite</topic><topic>Inductively coupled plasma</topic><topic>Klebsiella</topic><topic>Materials Science</topic><topic>Nitrates</topic><topic>Optical emission spectroscopy</topic><topic>Oxidizing agents</topic><topic>Pathogens</topic><topic>Potassium</topic><topic>Reducing agents</topic><topic>Scanning electron microscopy</topic><topic>Silica</topic><topic>Silicon</topic><topic>Sol-gel processes</topic><topic>Spectrum analysis</topic><topic>Sucrose</topic><topic>Tetraethyl orthosilicate</topic><topic>Transplants & implants</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MARY, M CHRISTE SONIA</creatorcontrib><creatorcontrib>CHATTERJEE, ANKITA</creatorcontrib><creatorcontrib>ABRAHAM, JAYANTHI</creatorcontrib><creatorcontrib>SASIKUMAR, S</creatorcontrib><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>SciTech Premium Collection</collection><collection>Materials Research Database</collection><collection>Materials Science Database</collection><collection>Materials Science Collection</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><jtitle>Bulletin of materials science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MARY, M CHRISTE SONIA</au><au>CHATTERJEE, ANKITA</au><au>ABRAHAM, JAYANTHI</au><au>SASIKUMAR, S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A study of the in-vitro bioactivity, dissolution and antibacterial activity of larnite prepared by a novel sol–gel combustion method using sucrose as a fuel</atitle><jtitle>Bulletin of materials science</jtitle><stitle>Bull Mater Sci</stitle><date>2020-12-01</date><risdate>2020</risdate><volume>43</volume><issue>1</issue><spage>237</spage><pages>237-</pages><artnum>237</artnum><issn>0250-4707</issn><eissn>0973-7669</eissn><abstract>This article presents the preparation and antibacterial activity of larnite bioceramics, an active calcium silicate ceramic material having the molecular formula Ca
2
SiO
4
. A stepwise sol–gel combustion approach was used to prepare the single phasic larnite. The synthesis of larnite was carried out with calcium nitrate tetrahydrate as a source of calcium which acts as an oxidizing agent and tetraethyl orthosilicate as a source of silicate which acts as a reducing agent (fuel). The powders thus prepared were calcined at temperatures ranging from 400 to 800°C. X-ray diffraction analysis was used to study the phase formation and determine the hydroxyapatite (HAP) formation during the bioactivity studies. The synthesized materials were also characterized by Fourier-transform infrared, scanning electron microscopy and energy dispersive X-ray techniques. Elemental ionic concentration of the Ca, P and Si in stimulated body fluid (SBF) solution was analysed by inductively coupled plasma-optical emission spectroscopy. The bone-like apatite formation ability of larnite scaffolds was investigated by immersing it in SBF. It was observed that larnite has the capability to deposit HAP within the early stage of immersion. The antimicrobial activity of the larnite was screened against nine clinical pathogens. The fabricated larnite compound was tested against both Gram-positive bacteria (
Staphylococcus aureus
and
Enterococcus
sp.) and Gram-negative bacteria (
Escherichia coli
,
Pseudomonas aeruginosa
,
Serratia marcescens
,
Shigella
sp.,
Proteus mirabilis
,
Salmonella
sp. and
Klebsiella pneumoniae
)
via
the agar diffusion method. The obtained results suggested that the prepared larnite has a high antibacterial property against Gram-negative bacteria because of its thin peptidoglycan layer. From the overall results it is concluded that larnite could be a promising candidate for biomedical applications.</abstract><cop>Bangalore</cop><pub>Indian Academy of Sciences</pub><doi>10.1007/s12034-020-02208-1</doi><orcidid>https://orcid.org/0000-0003-2533-4923</orcidid></addata></record> |
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| ispartof | Bulletin of materials science, 2020-12, Vol.43 (1), p.237, Article 237 |
| issn | 0250-4707 0973-7669 |
| language | eng |
| recordid | cdi_proquest_journals_2920220131 |
| source | Indian Academy of Sciences; SpringerLink Journals; EZB-FREE-00999 freely available EZB journals; Free Full-Text Journals in Chemistry; ProQuest Central |
| subjects | Apatite Bacterial infections Bioceramics Biological activity Biomedical materials Body fluids Calcium nitrate Chemistry and Materials Science Chloride Coliforms Combustion Decomposition Dicalcium silicate Drug resistance E coli Emission analysis Engineering Fourier transforms Fractures Fuels Hydroxyapatite Inductively coupled plasma Klebsiella Materials Science Nitrates Optical emission spectroscopy Oxidizing agents Pathogens Potassium Reducing agents Scanning electron microscopy Silica Silicon Sol-gel processes Spectrum analysis Sucrose Tetraethyl orthosilicate Transplants & implants |
| title | A study of the in-vitro bioactivity, dissolution and antibacterial activity of larnite prepared by a novel sol–gel combustion method using sucrose as a fuel |
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