Effect of High-Dose Metformin on the Metabolic Parameters and Functional State of the Liver of Agouti Mice with Melanocortin Obesity

The effectiveness of high-dose metformin (MF) for the treatment of endocrine and oncological diseases has been shown in recent years. However, the use of high-dose MF may be associated with lactic acidosis and liver dysfunctions. The goal of the work was to study the effect of long-term (10-day) ora...

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Veröffentlicht in:	Advances in gerontology 2020, Vol.10 (1), p.13-19
Hauptverfasser:	Derkach, K. V., Romanova, I. V., Zorina, I. I., Bakhtyukov, A. A., Perminova, A. A., Ivantsov, A. O., Shpakov, A. O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acidosis Diabetes Gene expression Geriatrics/Gerontology Glucose Homeostasis Insulin resistance Laboratory animals Liver Medicine Medicine & Public Health Metabolism Morphology Obesity Software
Online-Zugang:	Volltext
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