Laboratory Diagnostics of Ovarian Cancer among the Elderly Based on the Parameters of Immunoglobulins and Phagocytic Activity of Blood
New diagnostic methods are being sought for ovarian cancer due to its higher prevalence, which is the result of an increase in the share of elderly women. The purpose of this study was to analyze the content and sensitivity of immunoglobulins and the phagocytic activity of peripheral blood in order...
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| Veröffentlicht in: | Advances in gerontology 2020, Vol.10 (1), p.57-61 |
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| container_title | Advances in gerontology |
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| creator | Agarkov, N. M. Kicha, D. I. Harchenko, V. V. Koptev, D. S. Korovin, E. N. Blinkov, Yu. Yu Budnik, I. V. |
| description | New diagnostic methods are being sought for ovarian cancer due to its higher prevalence, which is the result of an increase in the share of elderly women. The purpose of this study was to analyze the content and sensitivity of immunoglobulins and the phagocytic activity of peripheral blood in order to improve the diagnostics of ovarian cancer among elderly women. The phagocytic activity and the immunoglobulin level in the peripheral blood were assessed with immunological and spectrophotometric methods in 78 patients with ovarian cancer aged 65–70 years. The control group comprised 42 women of the same age with no ovarian cancer. The primary importance of circulating immune complexes and the indices of neutrophil activity and the inhibition of phagocyte migration was established for laboratory diagnostics of ovarian cancer among elderly people. The use of highly informative parameters of systemic immunity may enhance the diagnostics of ovarian cancer in the elderly. |
| doi_str_mv | 10.1134/S2079057020010026 |
| format | Article |
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The primary importance of circulating immune complexes and the indices of neutrophil activity and the inhibition of phagocyte migration was established for laboratory diagnostics of ovarian cancer among elderly people. 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The phagocytic activity and the immunoglobulin level in the peripheral blood were assessed with immunological and spectrophotometric methods in 78 patients with ovarian cancer aged 65–70 years. The control group comprised 42 women of the same age with no ovarian cancer. The primary importance of circulating immune complexes and the indices of neutrophil activity and the inhibition of phagocyte migration was established for laboratory diagnostics of ovarian cancer among elderly people. The use of highly informative parameters of systemic immunity may enhance the diagnostics of ovarian cancer in the elderly.</description><subject>Antigens</subject><subject>Geriatrics/Gerontology</subject><subject>Immune system</subject><subject>Immunoglobulins</subject><subject>Immunology</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Neutrophils</subject><subject>Older people</subject><subject>Ovarian cancer</subject><subject>Statistical analysis</subject><issn>2079-0570</issn><issn>2079-0589</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kM9Kw0AQxhdRsNQ-gLcFz9XZzf9jW6sWCi2o5zDZbNKUZLfubgp5AZ_bpBU9iHOYGT6-3zcwhNwyuGfM8x9eOUQJBBFwAAbAwwsyGqQpBHFy-bNHcE0m1u6hrwB4BDAin2vMtEGnTUcfKyyVtq4SluqCbo5oKlR0gUpIQ7HRqqRuJ-myzqWpOzpHK3Oq1UncosFGOmlO7KppWqXLWmdtXSlLUeV0u8NSi66PpzPhqmPlusE6r7XOb8hVgbWVk-85Ju9Py7fFy3S9eV4tZuup4GHs-h6jCCDieRxhkTGfA3rcwyzEMAx8wXIZyzjPEubFrOAhB54kMgPBWBYx7ntjcnfOPRj90Urr0r1ujepPpjxhSQChx1nvYmeXMNpaI4v0YKoGTZcySIePp38-3jP8zNjeq0ppfpP_h74AJfSClQ</recordid><startdate>2020</startdate><enddate>2020</enddate><creator>Agarkov, N. 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| ispartof | Advances in gerontology, 2020, Vol.10 (1), p.57-61 |
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| subjects | Antigens Geriatrics/Gerontology Immune system Immunoglobulins Immunology Medicine Medicine & Public Health Neutrophils Older people Ovarian cancer Statistical analysis |
| title | Laboratory Diagnostics of Ovarian Cancer among the Elderly Based on the Parameters of Immunoglobulins and Phagocytic Activity of Blood |
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