Role of Liver Biopsy in the Era of Direct-Acting Antivirals
An accurate assessment of the degree of fibrosis or presence of cirrhosis is critical both for the appropriate management of, and to provide prognosis for, patients with chronic hepatitis C infection. In the new era of direct acting antivirals, large numbers of patients may enter therapy, and althou...
Gespeichert in:
| Veröffentlicht in: | Current gastroenterology reports 2013-02, Vol.15 (2), p.307, Article 307 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 2 |
| container_start_page | 307 |
| container_title | Current gastroenterology reports |
| container_volume | 15 |
| creator | Gonzalez, Humberto C. Jafri, Syed Mohammed Gordon, Stuart C |
| description | An accurate assessment of the degree of fibrosis or presence of cirrhosis is critical both for the appropriate management of, and to provide prognosis for, patients with chronic hepatitis C infection. In the new era of direct acting antivirals, large numbers of patients may enter therapy, and although liver biopsy remains the gold standard, it is not practical in all settings. In recent years, a variety of noninvasive methods have been developed that may obviate the need for liver biopsy in most settings. Indirect laboratory formulas, tests, panels of biomarkers and imaging modalities may accurately stage the degree of fibrosis in hepatitis C monoinfection, hepatitis C/HIV coinfection, and post-transplant recurrent hepatitis C. |
| doi_str_mv | 10.1007/s11894-012-0307-z |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2918763606</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2918763606</sourcerecordid><originalsourceid>FETCH-LOGICAL-c357z-498642bedd7a6d451ebbd7d5de7fdf8195ebe7f1cb685f4a24a7bbaba649a8393</originalsourceid><addsrcrecordid>eNp1kMtKAzEUhoMotlYfwI0MuI7mNkkGV7XWCxQEUXAXkkmmprQzNZkW2qc3w3hZufoP_JcDHwDnGF1hhMR1xFgWDCJMIKJIwP0BGOKcMkgxeT_sbkKgRFQMwEmMC4RIavFjMCCU4gJJPgQ3L83SZU2VzfzWhezWN-u4y3ydtR8umwbdWXc-uLKF47L19Twb163f-qCX8RQcVUnc2beOwNv99HXyCGfPD0-T8QyWNBd7yArJGTHOWqG5ZTl2xlhhc-tEZSuJi9yZdOLScJlXTBOmhTHaaM4KLWlBR-Cy312H5nPjYqsWzSbU6aUiBZaCU454SuE-VYYmxuAqtQ5-pcNOYaQ6XKrHpRIu1eFS-9S5-F7emJWzv40fPilA-kBMVj134e_1_6tfWAd1Eg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2918763606</pqid></control><display><type>article</type><title>Role of Liver Biopsy in the Era of Direct-Acting Antivirals</title><source>MEDLINE</source><source>ProQuest Central (Alumni Edition)</source><source>SpringerNature Journals</source><source>ProQuest Central UK/Ireland</source><source>ProQuest Central</source><creator>Gonzalez, Humberto C. ; Jafri, Syed Mohammed ; Gordon, Stuart C</creator><creatorcontrib>Gonzalez, Humberto C. ; Jafri, Syed Mohammed ; Gordon, Stuart C</creatorcontrib><description>An accurate assessment of the degree of fibrosis or presence of cirrhosis is critical both for the appropriate management of, and to provide prognosis for, patients with chronic hepatitis C infection. In the new era of direct acting antivirals, large numbers of patients may enter therapy, and although liver biopsy remains the gold standard, it is not practical in all settings. In recent years, a variety of noninvasive methods have been developed that may obviate the need for liver biopsy in most settings. Indirect laboratory formulas, tests, panels of biomarkers and imaging modalities may accurately stage the degree of fibrosis in hepatitis C monoinfection, hepatitis C/HIV coinfection, and post-transplant recurrent hepatitis C.</description><identifier>ISSN: 1522-8037</identifier><identifier>EISSN: 1534-312X</identifier><identifier>DOI: 10.1007/s11894-012-0307-z</identifier><identifier>PMID: 23319086</identifier><language>eng</language><publisher>New York: Current Science Inc</publisher><subject>Antiviral Agents - therapeutic use ; Biomarkers - blood ; Biopsy ; Disease ; Elasticity Imaging Techniques ; Gastroenterology ; Hemothorax ; Hepatitis B ; Hepatitis C ; Hepatitis C, Chronic - drug therapy ; Hepatitis C, Chronic - pathology ; HIV ; Human immunodeficiency virus ; Humans ; Hypotension ; Inflammation ; Liver (B Bacon ; Liver - pathology ; Liver cirrhosis ; Liver Cirrhosis - blood ; Liver Cirrhosis - diagnostic imaging ; Liver Cirrhosis - pathology ; Liver Cirrhosis - virology ; Liver transplants ; Magnetic Resonance Imaging ; Medicine ; Medicine & Public Health ; Pathology ; Patients ; Pneumothorax ; Sampling error ; Section Editor ; Severity of Illness Index ; Topical Collection on Liver</subject><ispartof>Current gastroenterology reports, 2013-02, Vol.15 (2), p.307, Article 307</ispartof><rights>Springer Science+Business Media New York 2013</rights><rights>Springer Science+Business Media New York 2013.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357z-498642bedd7a6d451ebbd7d5de7fdf8195ebe7f1cb685f4a24a7bbaba649a8393</citedby><cites>FETCH-LOGICAL-c357z-498642bedd7a6d451ebbd7d5de7fdf8195ebe7f1cb685f4a24a7bbaba649a8393</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11894-012-0307-z$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2918763606?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,21388,21389,27924,27925,33530,33744,41488,42557,43659,43805,51319,64385,64389,72469</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23319086$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gonzalez, Humberto C.</creatorcontrib><creatorcontrib>Jafri, Syed Mohammed</creatorcontrib><creatorcontrib>Gordon, Stuart C</creatorcontrib><title>Role of Liver Biopsy in the Era of Direct-Acting Antivirals</title><title>Current gastroenterology reports</title><addtitle>Curr Gastroenterol Rep</addtitle><addtitle>Curr Gastroenterol Rep</addtitle><description>An accurate assessment of the degree of fibrosis or presence of cirrhosis is critical both for the appropriate management of, and to provide prognosis for, patients with chronic hepatitis C infection. In the new era of direct acting antivirals, large numbers of patients may enter therapy, and although liver biopsy remains the gold standard, it is not practical in all settings. In recent years, a variety of noninvasive methods have been developed that may obviate the need for liver biopsy in most settings. Indirect laboratory formulas, tests, panels of biomarkers and imaging modalities may accurately stage the degree of fibrosis in hepatitis C monoinfection, hepatitis C/HIV coinfection, and post-transplant recurrent hepatitis C.</description><subject>Antiviral Agents - therapeutic use</subject><subject>Biomarkers - blood</subject><subject>Biopsy</subject><subject>Disease</subject><subject>Elasticity Imaging Techniques</subject><subject>Gastroenterology</subject><subject>Hemothorax</subject><subject>Hepatitis B</subject><subject>Hepatitis C</subject><subject>Hepatitis C, Chronic - drug therapy</subject><subject>Hepatitis C, Chronic - pathology</subject><subject>HIV</subject><subject>Human immunodeficiency virus</subject><subject>Humans</subject><subject>Hypotension</subject><subject>Inflammation</subject><subject>Liver (B Bacon</subject><subject>Liver - pathology</subject><subject>Liver cirrhosis</subject><subject>Liver Cirrhosis - blood</subject><subject>Liver Cirrhosis - diagnostic imaging</subject><subject>Liver Cirrhosis - pathology</subject><subject>Liver Cirrhosis - virology</subject><subject>Liver transplants</subject><subject>Magnetic Resonance Imaging</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Pathology</subject><subject>Patients</subject><subject>Pneumothorax</subject><subject>Sampling error</subject><subject>Section Editor</subject><subject>Severity of Illness Index</subject><subject>Topical Collection on Liver</subject><issn>1522-8037</issn><issn>1534-312X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kMtKAzEUhoMotlYfwI0MuI7mNkkGV7XWCxQEUXAXkkmmprQzNZkW2qc3w3hZufoP_JcDHwDnGF1hhMR1xFgWDCJMIKJIwP0BGOKcMkgxeT_sbkKgRFQMwEmMC4RIavFjMCCU4gJJPgQ3L83SZU2VzfzWhezWN-u4y3ydtR8umwbdWXc-uLKF47L19Twb163f-qCX8RQcVUnc2beOwNv99HXyCGfPD0-T8QyWNBd7yArJGTHOWqG5ZTl2xlhhc-tEZSuJi9yZdOLScJlXTBOmhTHaaM4KLWlBR-Cy312H5nPjYqsWzSbU6aUiBZaCU454SuE-VYYmxuAqtQ5-pcNOYaQ6XKrHpRIu1eFS-9S5-F7emJWzv40fPilA-kBMVj134e_1_6tfWAd1Eg</recordid><startdate>201302</startdate><enddate>201302</enddate><creator>Gonzalez, Humberto C.</creator><creator>Jafri, Syed Mohammed</creator><creator>Gordon, Stuart C</creator><general>Current Science Inc</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope></search><sort><creationdate>201302</creationdate><title>Role of Liver Biopsy in the Era of Direct-Acting Antivirals</title><author>Gonzalez, Humberto C. ; Jafri, Syed Mohammed ; Gordon, Stuart C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357z-498642bedd7a6d451ebbd7d5de7fdf8195ebe7f1cb685f4a24a7bbaba649a8393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Antiviral Agents - therapeutic use</topic><topic>Biomarkers - blood</topic><topic>Biopsy</topic><topic>Disease</topic><topic>Elasticity Imaging Techniques</topic><topic>Gastroenterology</topic><topic>Hemothorax</topic><topic>Hepatitis B</topic><topic>Hepatitis C</topic><topic>Hepatitis C, Chronic - drug therapy</topic><topic>Hepatitis C, Chronic - pathology</topic><topic>HIV</topic><topic>Human immunodeficiency virus</topic><topic>Humans</topic><topic>Hypotension</topic><topic>Inflammation</topic><topic>Liver (B Bacon</topic><topic>Liver - pathology</topic><topic>Liver cirrhosis</topic><topic>Liver Cirrhosis - blood</topic><topic>Liver Cirrhosis - diagnostic imaging</topic><topic>Liver Cirrhosis - pathology</topic><topic>Liver Cirrhosis - virology</topic><topic>Liver transplants</topic><topic>Magnetic Resonance Imaging</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Pathology</topic><topic>Patients</topic><topic>Pneumothorax</topic><topic>Sampling error</topic><topic>Section Editor</topic><topic>Severity of Illness Index</topic><topic>Topical Collection on Liver</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gonzalez, Humberto C.</creatorcontrib><creatorcontrib>Jafri, Syed Mohammed</creatorcontrib><creatorcontrib>Gordon, Stuart C</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><jtitle>Current gastroenterology reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gonzalez, Humberto C.</au><au>Jafri, Syed Mohammed</au><au>Gordon, Stuart C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Role of Liver Biopsy in the Era of Direct-Acting Antivirals</atitle><jtitle>Current gastroenterology reports</jtitle><stitle>Curr Gastroenterol Rep</stitle><addtitle>Curr Gastroenterol Rep</addtitle><date>2013-02</date><risdate>2013</risdate><volume>15</volume><issue>2</issue><spage>307</spage><pages>307-</pages><artnum>307</artnum><issn>1522-8037</issn><eissn>1534-312X</eissn><abstract>An accurate assessment of the degree of fibrosis or presence of cirrhosis is critical both for the appropriate management of, and to provide prognosis for, patients with chronic hepatitis C infection. In the new era of direct acting antivirals, large numbers of patients may enter therapy, and although liver biopsy remains the gold standard, it is not practical in all settings. In recent years, a variety of noninvasive methods have been developed that may obviate the need for liver biopsy in most settings. Indirect laboratory formulas, tests, panels of biomarkers and imaging modalities may accurately stage the degree of fibrosis in hepatitis C monoinfection, hepatitis C/HIV coinfection, and post-transplant recurrent hepatitis C.</abstract><cop>New York</cop><pub>Current Science Inc</pub><pmid>23319086</pmid><doi>10.1007/s11894-012-0307-z</doi></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1522-8037 |
| ispartof | Current gastroenterology reports, 2013-02, Vol.15 (2), p.307, Article 307 |
| issn | 1522-8037 1534-312X |
| language | eng |
| recordid | cdi_proquest_journals_2918763606 |
| source | MEDLINE; ProQuest Central (Alumni Edition); SpringerNature Journals; ProQuest Central UK/Ireland; ProQuest Central |
| subjects | Antiviral Agents - therapeutic use Biomarkers - blood Biopsy Disease Elasticity Imaging Techniques Gastroenterology Hemothorax Hepatitis B Hepatitis C Hepatitis C, Chronic - drug therapy Hepatitis C, Chronic - pathology HIV Human immunodeficiency virus Humans Hypotension Inflammation Liver (B Bacon Liver - pathology Liver cirrhosis Liver Cirrhosis - blood Liver Cirrhosis - diagnostic imaging Liver Cirrhosis - pathology Liver Cirrhosis - virology Liver transplants Magnetic Resonance Imaging Medicine Medicine & Public Health Pathology Patients Pneumothorax Sampling error Section Editor Severity of Illness Index Topical Collection on Liver |
| title | Role of Liver Biopsy in the Era of Direct-Acting Antivirals |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T04%3A01%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Role%20of%20Liver%20Biopsy%20in%20the%20Era%20of%20Direct-Acting%20Antivirals&rft.jtitle=Current%20gastroenterology%20reports&rft.au=Gonzalez,%20Humberto%20C.&rft.date=2013-02&rft.volume=15&rft.issue=2&rft.spage=307&rft.pages=307-&rft.artnum=307&rft.issn=1522-8037&rft.eissn=1534-312X&rft_id=info:doi/10.1007/s11894-012-0307-z&rft_dat=%3Cproquest_cross%3E2918763606%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2918763606&rft_id=info:pmid/23319086&rfr_iscdi=true |