Clinical observation on heat-sensitive moxibustion plus lactulose for postoperative constipation of mixed hemorrhoid due to spleen deficiency

Objective To observe the clinical effect of heat-sensitive moxibustion plus lactulose oral liquid for postoperative constipation of mixed hemorrhoid. Methods A total of 70 patients were randomized into a treatment group and a control group, with 35 cases in each group by a random number table. Patie...

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Veröffentlicht in:Journal of acupuncture and tuina science 2020-06, Vol.18 (3), p.219-224
Hauptverfasser: Dong, Fen-fen, Ying, Jian
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description Objective To observe the clinical effect of heat-sensitive moxibustion plus lactulose oral liquid for postoperative constipation of mixed hemorrhoid. Methods A total of 70 patients were randomized into a treatment group and a control group, with 35 cases in each group by a random number table. Patients in the control group received lactulose oral liquid alone, while those in the treatment group received additional heat-sensitive moxibustion at Shenque (CV 8). The treatment was given once a day for 15 consecutive days. The defecation interval time, defecation duration, the scores of stool form, visual analog scale (VAS) and patient assessment of constipation quality of life questionnaire (PAC-QOL), as well as the serum substance P (SP) and nitric oxide (NO) levels were measured before and after treatment. Results After treatment, the stool form score, defecation interval time and defecation duration in the two groups dropped significantly (all P
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Methods A total of 70 patients were randomized into a treatment group and a control group, with 35 cases in each group by a random number table. Patients in the control group received lactulose oral liquid alone, while those in the treatment group received additional heat-sensitive moxibustion at Shenque (CV 8). The treatment was given once a day for 15 consecutive days. The defecation interval time, defecation duration, the scores of stool form, visual analog scale (VAS) and patient assessment of constipation quality of life questionnaire (PAC-QOL), as well as the serum substance P (SP) and nitric oxide (NO) levels were measured before and after treatment. Results After treatment, the stool form score, defecation interval time and defecation duration in the two groups dropped significantly (all P <0.05), and they were lower in the treatment group than in the control group (all P <0.05). After treatment, the VAS scores in the two groups dropped significantly (both P <0.05), and it was lower in the treatment group than in the control group ( P <0.05). After treatment, the PAC-QOL scores in the two groups dropped significantly (both P <0.05), and it was lower in the treatment group than in the control group ( P <0.05). After treatment, the serum SP and NO levels in the two groups improved significantly (all P <0.05), and showed statistically significant differences between the treatment group and the control group (both P <0.05). Conclusion Heat-sensitive moxibustion plus lactulose oral liquid can improve stool form, shorten defecation interval time and defecation duration, alleviate defecation pain, and improve quality of life (QOL) for patients with postoperative constipation of mixed hemorrhoid, which may be related to the regulation of the SP and NO levels.]]></description><identifier>ISSN: 1672-3597</identifier><identifier>EISSN: 1993-0399</identifier><identifier>DOI: 10.1007/s11726-020-1181-0</identifier><language>eng</language><publisher>Singapore: Springer Singapore</publisher><subject>Acupuncture ; Clinical Study ; Constipation ; Defecation ; Hemorrhoids ; Medicine ; Medicine &amp; Public Health ; Quality of life</subject><ispartof>Journal of acupuncture and tuina science, 2020-06, Vol.18 (3), p.219-224</ispartof><rights>Shanghai Research Institute of Acupuncture and Meridian 2020</rights><rights>Shanghai Research Institute of Acupuncture and Meridian 2020.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c268t-cffe4e5c516d38e0174c724dcfb393f5033d2983a7dcfb921ef6b851acd3f0a03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11726-020-1181-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2918735388?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,778,782,21371,21372,23239,27907,27908,33513,33686,33727,41471,42540,43642,43770,43788,51302,64366,64370,72220</link.rule.ids></links><search><creatorcontrib>Dong, Fen-fen</creatorcontrib><creatorcontrib>Ying, Jian</creatorcontrib><title>Clinical observation on heat-sensitive moxibustion plus lactulose for postoperative constipation of mixed hemorrhoid due to spleen deficiency</title><title>Journal of acupuncture and tuina science</title><addtitle>J. Acupunct. Tuina. Sci</addtitle><description><![CDATA[Objective To observe the clinical effect of heat-sensitive moxibustion plus lactulose oral liquid for postoperative constipation of mixed hemorrhoid. Methods A total of 70 patients were randomized into a treatment group and a control group, with 35 cases in each group by a random number table. Patients in the control group received lactulose oral liquid alone, while those in the treatment group received additional heat-sensitive moxibustion at Shenque (CV 8). The treatment was given once a day for 15 consecutive days. The defecation interval time, defecation duration, the scores of stool form, visual analog scale (VAS) and patient assessment of constipation quality of life questionnaire (PAC-QOL), as well as the serum substance P (SP) and nitric oxide (NO) levels were measured before and after treatment. Results After treatment, the stool form score, defecation interval time and defecation duration in the two groups dropped significantly (all P <0.05), and they were lower in the treatment group than in the control group (all P <0.05). After treatment, the VAS scores in the two groups dropped significantly (both P <0.05), and it was lower in the treatment group than in the control group ( P <0.05). After treatment, the PAC-QOL scores in the two groups dropped significantly (both P <0.05), and it was lower in the treatment group than in the control group ( P <0.05). After treatment, the serum SP and NO levels in the two groups improved significantly (all P <0.05), and showed statistically significant differences between the treatment group and the control group (both P <0.05). Conclusion Heat-sensitive moxibustion plus lactulose oral liquid can improve stool form, shorten defecation interval time and defecation duration, alleviate defecation pain, and improve quality of life (QOL) for patients with postoperative constipation of mixed hemorrhoid, which may be related to the regulation of the SP and NO levels.]]></description><subject>Acupuncture</subject><subject>Clinical Study</subject><subject>Constipation</subject><subject>Defecation</subject><subject>Hemorrhoids</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Quality of life</subject><issn>1672-3597</issn><issn>1993-0399</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kF1LwzAUhosoOKc_wLuA19F8rE1yKcMvGHij1yFNT1xG29SkHduP8D_bbgOvhEDCOc_7BN4su6XknhIiHhKlghWYMIIplRSTs2xGleKYcKXOx3chGOa5EpfZVUobQnJRMDbLfpa1b701NQplgrg1vQ8tGs8aTI8TtMn3fguoCTtfDumw7eohodrYfqhDAuRCRF1IfeggmgNsQzuS3cnlUON3UI3GJsS4Dr5C1QCoDyh1NUCLKnDeemjt_jq7cKZOcHO659nn89PH8hWv3l_elo8rbFkhe2ydgwXkNqdFxSUQKhZWsEVlXckVdznhvGJKciOmkWIUXFHKnBpbcUcM4fPs7ujtYvgeIPV6E4bYjl9qpqgUPOdSjhQ9UjaGlCI43UXfmLjXlOipdX1sXY-t66l1PZnZMZNGtv2C-Gf-P_QLtzSJvg</recordid><startdate>20200601</startdate><enddate>20200601</enddate><creator>Dong, Fen-fen</creator><creator>Ying, Jian</creator><general>Springer Singapore</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>M0R</scope><scope>M0S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope></search><sort><creationdate>20200601</creationdate><title>Clinical observation on heat-sensitive moxibustion plus lactulose for postoperative constipation of mixed hemorrhoid due to spleen deficiency</title><author>Dong, Fen-fen ; Ying, Jian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c268t-cffe4e5c516d38e0174c724dcfb393f5033d2983a7dcfb921ef6b851acd3f0a03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Acupuncture</topic><topic>Clinical Study</topic><topic>Constipation</topic><topic>Defecation</topic><topic>Hemorrhoids</topic><topic>Medicine</topic><topic>Medicine &amp; Public Health</topic><topic>Quality of life</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dong, Fen-fen</creatorcontrib><creatorcontrib>Ying, Jian</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Consumer Health Database</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><jtitle>Journal of acupuncture and tuina science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dong, Fen-fen</au><au>Ying, Jian</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical observation on heat-sensitive moxibustion plus lactulose for postoperative constipation of mixed hemorrhoid due to spleen deficiency</atitle><jtitle>Journal of acupuncture and tuina science</jtitle><stitle>J. Acupunct. Tuina. Sci</stitle><date>2020-06-01</date><risdate>2020</risdate><volume>18</volume><issue>3</issue><spage>219</spage><epage>224</epage><pages>219-224</pages><issn>1672-3597</issn><eissn>1993-0399</eissn><abstract><![CDATA[Objective To observe the clinical effect of heat-sensitive moxibustion plus lactulose oral liquid for postoperative constipation of mixed hemorrhoid. Methods A total of 70 patients were randomized into a treatment group and a control group, with 35 cases in each group by a random number table. Patients in the control group received lactulose oral liquid alone, while those in the treatment group received additional heat-sensitive moxibustion at Shenque (CV 8). The treatment was given once a day for 15 consecutive days. The defecation interval time, defecation duration, the scores of stool form, visual analog scale (VAS) and patient assessment of constipation quality of life questionnaire (PAC-QOL), as well as the serum substance P (SP) and nitric oxide (NO) levels were measured before and after treatment. Results After treatment, the stool form score, defecation interval time and defecation duration in the two groups dropped significantly (all P <0.05), and they were lower in the treatment group than in the control group (all P <0.05). After treatment, the VAS scores in the two groups dropped significantly (both P <0.05), and it was lower in the treatment group than in the control group ( P <0.05). After treatment, the PAC-QOL scores in the two groups dropped significantly (both P <0.05), and it was lower in the treatment group than in the control group ( P <0.05). After treatment, the serum SP and NO levels in the two groups improved significantly (all P <0.05), and showed statistically significant differences between the treatment group and the control group (both P <0.05). Conclusion Heat-sensitive moxibustion plus lactulose oral liquid can improve stool form, shorten defecation interval time and defecation duration, alleviate defecation pain, and improve quality of life (QOL) for patients with postoperative constipation of mixed hemorrhoid, which may be related to the regulation of the SP and NO levels.]]></abstract><cop>Singapore</cop><pub>Springer Singapore</pub><doi>10.1007/s11726-020-1181-0</doi><tpages>6</tpages></addata></record>
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subjects Acupuncture
Clinical Study
Constipation
Defecation
Hemorrhoids
Medicine
Medicine & Public Health
Quality of life
title Clinical observation on heat-sensitive moxibustion plus lactulose for postoperative constipation of mixed hemorrhoid due to spleen deficiency
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