Off-pump coronary artery bypass grafting in a patient with paroxysmal nocturnal hemoglobinuria
Paroxysmal nocturnal hemoglobinuria has not been described in patients undergoing off-pump coronary artery bypass grafting. A 65-year-old man who underwent percutaneous coronary stenting to the proximal left anterior descending artery for unstable angina was readmitted to our hospital complaining of...
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Veröffentlicht in: | General thoracic and cardiovascular surgery 2004-10, Vol.52 (10), p.469-472 |
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description | Paroxysmal nocturnal hemoglobinuria has not been described in patients undergoing off-pump coronary artery bypass grafting. A 65-year-old man who underwent percutaneous coronary stenting to the proximal left anterior descending artery for unstable angina was readmitted to our hospital complaining of recurrent chest pains. A coronary angiography revealed in-stent restenosis and new lesions of the distal left anterior descending artery as well as the left circumflex artery branch. He was found to have paroxysmal nocturnal hemoglobinuria which contributes to serious surgical complications including infection, bleeding, hemolysis and acute renal failure. After pancytopenia was treated with administration of granulocyte colony stimulating factor and transfusion of the washed red blood cells preoperatively, off-pump coronary artery bypass grafting was performed. Cardiopulmonary bypass was avoided in order to reduce activation of complements. His postoperative course was uneventful. Combination of appropriate perioperative management and off-pump cardiac surgery yielded an effective result in treating this patient without major complications. |
doi_str_mv | 10.1007/s11748-004-0142-8 |
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A 65-year-old man who underwent percutaneous coronary stenting to the proximal left anterior descending artery for unstable angina was readmitted to our hospital complaining of recurrent chest pains. A coronary angiography revealed in-stent restenosis and new lesions of the distal left anterior descending artery as well as the left circumflex artery branch. He was found to have paroxysmal nocturnal hemoglobinuria which contributes to serious surgical complications including infection, bleeding, hemolysis and acute renal failure. After pancytopenia was treated with administration of granulocyte colony stimulating factor and transfusion of the washed red blood cells preoperatively, off-pump coronary artery bypass grafting was performed. Cardiopulmonary bypass was avoided in order to reduce activation of complements. His postoperative course was uneventful. Combination of appropriate perioperative management and off-pump cardiac surgery yielded an effective result in treating this patient without major complications.</description><identifier>ISSN: 1344-4964</identifier><identifier>ISSN: 1863-6705</identifier><identifier>EISSN: 1863-2092</identifier><identifier>EISSN: 1863-6713</identifier><identifier>DOI: 10.1007/s11748-004-0142-8</identifier><identifier>PMID: 15552971</identifier><language>eng</language><publisher>Japan: Springer Nature B.V</publisher><subject>Aged ; Angina, Unstable - surgery ; Coronary Artery Bypass - methods ; Coronary vessels ; Heart surgery ; Hemoglobinuria, Paroxysmal - complications ; Humans ; Male ; Stents ; Veins & arteries</subject><ispartof>General thoracic and cardiovascular surgery, 2004-10, Vol.52 (10), p.469-472</ispartof><rights>Japanese Association for Thoracic Surgery 2004.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c293t-ee71a2fb617d68f0886584788080cc62a94592725de4783c3d3158ba3dbe97b93</citedby><cites>FETCH-LOGICAL-c293t-ee71a2fb617d68f0886584788080cc62a94592725de4783c3d3158ba3dbe97b93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/2918734886?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,776,780,21367,27901,27902,33721,43781</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15552971$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Makino, Yutaka</creatorcontrib><creatorcontrib>Suto, Yukio</creatorcontrib><creatorcontrib>Murakami, Tatsuya</creatorcontrib><title>Off-pump coronary artery bypass grafting in a patient with paroxysmal nocturnal hemoglobinuria</title><title>General thoracic and cardiovascular surgery</title><addtitle>Jpn J Thorac Cardiovasc Surg</addtitle><description>Paroxysmal nocturnal hemoglobinuria has not been described in patients undergoing off-pump coronary artery bypass grafting. A 65-year-old man who underwent percutaneous coronary stenting to the proximal left anterior descending artery for unstable angina was readmitted to our hospital complaining of recurrent chest pains. A coronary angiography revealed in-stent restenosis and new lesions of the distal left anterior descending artery as well as the left circumflex artery branch. He was found to have paroxysmal nocturnal hemoglobinuria which contributes to serious surgical complications including infection, bleeding, hemolysis and acute renal failure. After pancytopenia was treated with administration of granulocyte colony stimulating factor and transfusion of the washed red blood cells preoperatively, off-pump coronary artery bypass grafting was performed. Cardiopulmonary bypass was avoided in order to reduce activation of complements. His postoperative course was uneventful. Combination of appropriate perioperative management and off-pump cardiac surgery yielded an effective result in treating this patient without major complications.</description><subject>Aged</subject><subject>Angina, Unstable - surgery</subject><subject>Coronary Artery Bypass - methods</subject><subject>Coronary vessels</subject><subject>Heart surgery</subject><subject>Hemoglobinuria, Paroxysmal - complications</subject><subject>Humans</subject><subject>Male</subject><subject>Stents</subject><subject>Veins & arteries</subject><issn>1344-4964</issn><issn>1863-6705</issn><issn>1863-2092</issn><issn>1863-6713</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNpdkMlKxDAYgIMojo4-gBcpCN6i2ZejDG4geNGrIW3TmQ5tUpMWnbc34wwInv6F71_4ALjA6AYjJG8TxpIpiBCDCDMC1QE4wUpQSJAmhzmnjEGmBZuB05TWmZNc6mMww5xzoiU-AR-vTQOHqR-KKsTgbdwUNo4uh3Iz2JSKZbTN2Ppl0frCFoMdW-fH4qsdV7mI4XuTetsVPlTjFH3OVq4Pyy6UrZ9ia8_AUWO75M73cQ7eH-7fFk_w5fXxeXH3Aiui6Qidk9iSphRY1kI1SCnBFZNKIYWqShCrGddEEl673KUVrSnmqrS0Lp2WpaZzcL3bO8TwObk0mr5Nles6612YkhESSSKlyODVP3Adfh9PhmisJGX5dqbwjqpiSCm6xgyx7bMcg5HZqjc79SYrNVv1RuWZy_3mqexd_Texd01_AJ0Qf0k</recordid><startdate>200410</startdate><enddate>200410</enddate><creator>Makino, Yutaka</creator><creator>Suto, Yukio</creator><creator>Murakami, Tatsuya</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope></search><sort><creationdate>200410</creationdate><title>Off-pump coronary artery bypass grafting in a patient with paroxysmal nocturnal hemoglobinuria</title><author>Makino, Yutaka ; Suto, Yukio ; Murakami, Tatsuya</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c293t-ee71a2fb617d68f0886584788080cc62a94592725de4783c3d3158ba3dbe97b93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Aged</topic><topic>Angina, Unstable - surgery</topic><topic>Coronary Artery Bypass - methods</topic><topic>Coronary vessels</topic><topic>Heart surgery</topic><topic>Hemoglobinuria, Paroxysmal - complications</topic><topic>Humans</topic><topic>Male</topic><topic>Stents</topic><topic>Veins & arteries</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Makino, Yutaka</creatorcontrib><creatorcontrib>Suto, Yukio</creatorcontrib><creatorcontrib>Murakami, Tatsuya</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>General thoracic and cardiovascular surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Makino, Yutaka</au><au>Suto, Yukio</au><au>Murakami, Tatsuya</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Off-pump coronary artery bypass grafting in a patient with paroxysmal nocturnal hemoglobinuria</atitle><jtitle>General thoracic and cardiovascular surgery</jtitle><addtitle>Jpn J Thorac Cardiovasc Surg</addtitle><date>2004-10</date><risdate>2004</risdate><volume>52</volume><issue>10</issue><spage>469</spage><epage>472</epage><pages>469-472</pages><issn>1344-4964</issn><issn>1863-6705</issn><eissn>1863-2092</eissn><eissn>1863-6713</eissn><abstract>Paroxysmal nocturnal hemoglobinuria has not been described in patients undergoing off-pump coronary artery bypass grafting. A 65-year-old man who underwent percutaneous coronary stenting to the proximal left anterior descending artery for unstable angina was readmitted to our hospital complaining of recurrent chest pains. A coronary angiography revealed in-stent restenosis and new lesions of the distal left anterior descending artery as well as the left circumflex artery branch. He was found to have paroxysmal nocturnal hemoglobinuria which contributes to serious surgical complications including infection, bleeding, hemolysis and acute renal failure. After pancytopenia was treated with administration of granulocyte colony stimulating factor and transfusion of the washed red blood cells preoperatively, off-pump coronary artery bypass grafting was performed. Cardiopulmonary bypass was avoided in order to reduce activation of complements. His postoperative course was uneventful. Combination of appropriate perioperative management and off-pump cardiac surgery yielded an effective result in treating this patient without major complications.</abstract><cop>Japan</cop><pub>Springer Nature B.V</pub><pmid>15552971</pmid><doi>10.1007/s11748-004-0142-8</doi><tpages>4</tpages></addata></record> |
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subjects | Aged Angina, Unstable - surgery Coronary Artery Bypass - methods Coronary vessels Heart surgery Hemoglobinuria, Paroxysmal - complications Humans Male Stents Veins & arteries |
title | Off-pump coronary artery bypass grafting in a patient with paroxysmal nocturnal hemoglobinuria |
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