Outcome of a pulmonary metastasectomy for an orthopedic malignancy
The purpose of this study was to examine the pulmonary metastatic results in patients with orthopedic malignancies. Forty-three consecutive patients who underwent a resection of a pulmonary metastasis from an orthopedic malignancy in our hospital were retrospectively investigated. The survival follo...
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| Veröffentlicht in: | General thoracic and cardiovascular surgery 2005-08, Vol.53 (8), p.420-425 |
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| creator | Suemitsu, Ryuichi Yoshino, Ichiro Tomiyasu, Makiko Ondo, Kaoru Ueda, Hitoshi Iwamoto, Yukihide Maehara, Yoshihiko |
| description | The purpose of this study was to examine the pulmonary metastatic results in patients with orthopedic malignancies.
Forty-three consecutive patients who underwent a resection of a pulmonary metastasis from an orthopedic malignancy in our hospital were retrospectively investigated. The survival following the resection of a pulmonary metastatic tumor was then analyzed using the Kaplan-Meier method. The impact of clinicopathologic variables on the prognosis including gender, patient age, primary tumor type, the number of the pulmonary metastases, the number of metastasectomies, the operation-era, and the disease-free interval was examined by the Logrank test and Cox's proportional hazards model.
The 5-year overall survivals after a pulmonary metastasectomy were 20.7%. A univariate analysis revealed a significant benefit in the post-metastasectomy survival based on the patients age and the disease-free interval. A multivariate analysis demonstrated patient age to be an independent factor for the prognosis with a hazard ratio of 4.873 (p = 0.0373). When only young (less than 40 years of age) patients were investigated, the histologic type was revealed to be related to the prognosis (p = 0.0004).
Pulmonary metastasis from soft tissue tumors is considered to lead to a poor prognosis for younger patients and a metastasectomy for such patients should be considered as one of the potentially effective treatments. |
| doi_str_mv | 10.1007/s11748-005-0077-8 |
| format | Article |
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Forty-three consecutive patients who underwent a resection of a pulmonary metastasis from an orthopedic malignancy in our hospital were retrospectively investigated. The survival following the resection of a pulmonary metastatic tumor was then analyzed using the Kaplan-Meier method. The impact of clinicopathologic variables on the prognosis including gender, patient age, primary tumor type, the number of the pulmonary metastases, the number of metastasectomies, the operation-era, and the disease-free interval was examined by the Logrank test and Cox's proportional hazards model.
The 5-year overall survivals after a pulmonary metastasectomy were 20.7%. A univariate analysis revealed a significant benefit in the post-metastasectomy survival based on the patients age and the disease-free interval. A multivariate analysis demonstrated patient age to be an independent factor for the prognosis with a hazard ratio of 4.873 (p = 0.0373). When only young (less than 40 years of age) patients were investigated, the histologic type was revealed to be related to the prognosis (p = 0.0004).
Pulmonary metastasis from soft tissue tumors is considered to lead to a poor prognosis for younger patients and a metastasectomy for such patients should be considered as one of the potentially effective treatments.</description><identifier>ISSN: 1344-4964</identifier><identifier>ISSN: 1863-6705</identifier><identifier>EISSN: 1863-2092</identifier><identifier>EISSN: 1863-6713</identifier><identifier>DOI: 10.1007/s11748-005-0077-8</identifier><identifier>PMID: 16164253</identifier><language>eng</language><publisher>Japan: Springer Nature B.V</publisher><subject>Adolescent ; Adult ; Bone Neoplasms - pathology ; Child ; Combined Modality Therapy ; Female ; Humans ; Lung cancer ; Lung Neoplasms - mortality ; Lung Neoplasms - secondary ; Lung Neoplasms - surgery ; Male ; Medical prognosis ; Metastasis ; Middle Aged ; Orthopedics ; Patients ; Pneumonectomy - mortality ; Retrospective Studies ; Sarcoma - mortality ; Sarcoma - secondary ; Sarcoma - surgery ; Survival Analysis ; Treatment Outcome</subject><ispartof>General thoracic and cardiovascular surgery, 2005-08, Vol.53 (8), p.420-425</ispartof><rights>Japanese Association for Thoracic Surgery 2005.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c446t-bbae51b4e65d2c84d338cde689a45cd03b0a1cb76b20bc293dad24bbbfda7f8b3</citedby><cites>FETCH-LOGICAL-c446t-bbae51b4e65d2c84d338cde689a45cd03b0a1cb76b20bc293dad24bbbfda7f8b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/2918733723?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,21388,21389,27924,27925,33530,33744,43659,43805,64385,64389,72341</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16164253$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Suemitsu, Ryuichi</creatorcontrib><creatorcontrib>Yoshino, Ichiro</creatorcontrib><creatorcontrib>Tomiyasu, Makiko</creatorcontrib><creatorcontrib>Ondo, Kaoru</creatorcontrib><creatorcontrib>Ueda, Hitoshi</creatorcontrib><creatorcontrib>Iwamoto, Yukihide</creatorcontrib><creatorcontrib>Maehara, Yoshihiko</creatorcontrib><title>Outcome of a pulmonary metastasectomy for an orthopedic malignancy</title><title>General thoracic and cardiovascular surgery</title><addtitle>Jpn J Thorac Cardiovasc Surg</addtitle><description>The purpose of this study was to examine the pulmonary metastatic results in patients with orthopedic malignancies.
Forty-three consecutive patients who underwent a resection of a pulmonary metastasis from an orthopedic malignancy in our hospital were retrospectively investigated. The survival following the resection of a pulmonary metastatic tumor was then analyzed using the Kaplan-Meier method. The impact of clinicopathologic variables on the prognosis including gender, patient age, primary tumor type, the number of the pulmonary metastases, the number of metastasectomies, the operation-era, and the disease-free interval was examined by the Logrank test and Cox's proportional hazards model.
The 5-year overall survivals after a pulmonary metastasectomy were 20.7%. A univariate analysis revealed a significant benefit in the post-metastasectomy survival based on the patients age and the disease-free interval. A multivariate analysis demonstrated patient age to be an independent factor for the prognosis with a hazard ratio of 4.873 (p = 0.0373). When only young (less than 40 years of age) patients were investigated, the histologic type was revealed to be related to the prognosis (p = 0.0004).
Pulmonary metastasis from soft tissue tumors is considered to lead to a poor prognosis for younger patients and a metastasectomy for such patients should be considered as one of the potentially effective treatments.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Bone Neoplasms - pathology</subject><subject>Child</subject><subject>Combined Modality Therapy</subject><subject>Female</subject><subject>Humans</subject><subject>Lung cancer</subject><subject>Lung Neoplasms - mortality</subject><subject>Lung Neoplasms - secondary</subject><subject>Lung Neoplasms - surgery</subject><subject>Male</subject><subject>Medical prognosis</subject><subject>Metastasis</subject><subject>Middle Aged</subject><subject>Orthopedics</subject><subject>Patients</subject><subject>Pneumonectomy - mortality</subject><subject>Retrospective Studies</subject><subject>Sarcoma - mortality</subject><subject>Sarcoma - secondary</subject><subject>Sarcoma - surgery</subject><subject>Survival Analysis</subject><subject>Treatment Outcome</subject><issn>1344-4964</issn><issn>1863-6705</issn><issn>1863-2092</issn><issn>1863-6713</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpdkEtLAzEUhYMotlZ_gBsJCO5G85oks9TiCwrd6DrkNTplMqnJzKL_3pQWBOFe7l2cc7j3A-Aao3uMkHjIGAsmK4Tq0kJU8gTMseS0Iqghp2WnjFWs4WwGLnLeIMRELZpzMMMcc0ZqOgdP62m0MXgYW6jhdupDHHTaweBHnUt5O8awg21MUA8wpvE7br3rLAy6774GPdjdJThrdZ_91XEuwOfL88fyrVqtX9-Xj6vKMsbHyhjta2yY57UjVjJHqbTOc9loVluHqEEaWyO4IchY0lCnHWHGmNZp0UpDF-DukLtN8WfyeVShy9b3vR58nLLism4Iw7gIb_8JN3FKQ7lNkQZLQakgtKjwQWVTzDn5Vm1TF8rvCiO1x6sOeFXBq_Z4lSyem2PyZIJ3f44jT_oL4t52bQ</recordid><startdate>20050801</startdate><enddate>20050801</enddate><creator>Suemitsu, Ryuichi</creator><creator>Yoshino, Ichiro</creator><creator>Tomiyasu, Makiko</creator><creator>Ondo, Kaoru</creator><creator>Ueda, Hitoshi</creator><creator>Iwamoto, Yukihide</creator><creator>Maehara, Yoshihiko</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope></search><sort><creationdate>20050801</creationdate><title>Outcome of a pulmonary metastasectomy for an orthopedic malignancy</title><author>Suemitsu, Ryuichi ; Yoshino, Ichiro ; Tomiyasu, Makiko ; Ondo, Kaoru ; Ueda, Hitoshi ; Iwamoto, Yukihide ; Maehara, Yoshihiko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c446t-bbae51b4e65d2c84d338cde689a45cd03b0a1cb76b20bc293dad24bbbfda7f8b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Bone Neoplasms - pathology</topic><topic>Child</topic><topic>Combined Modality Therapy</topic><topic>Female</topic><topic>Humans</topic><topic>Lung cancer</topic><topic>Lung Neoplasms - mortality</topic><topic>Lung Neoplasms - secondary</topic><topic>Lung Neoplasms - surgery</topic><topic>Male</topic><topic>Medical prognosis</topic><topic>Metastasis</topic><topic>Middle Aged</topic><topic>Orthopedics</topic><topic>Patients</topic><topic>Pneumonectomy - mortality</topic><topic>Retrospective Studies</topic><topic>Sarcoma - mortality</topic><topic>Sarcoma - secondary</topic><topic>Sarcoma - surgery</topic><topic>Survival Analysis</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Suemitsu, Ryuichi</creatorcontrib><creatorcontrib>Yoshino, Ichiro</creatorcontrib><creatorcontrib>Tomiyasu, Makiko</creatorcontrib><creatorcontrib>Ondo, Kaoru</creatorcontrib><creatorcontrib>Ueda, Hitoshi</creatorcontrib><creatorcontrib>Iwamoto, Yukihide</creatorcontrib><creatorcontrib>Maehara, Yoshihiko</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>General thoracic and cardiovascular surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Suemitsu, Ryuichi</au><au>Yoshino, Ichiro</au><au>Tomiyasu, Makiko</au><au>Ondo, Kaoru</au><au>Ueda, Hitoshi</au><au>Iwamoto, Yukihide</au><au>Maehara, Yoshihiko</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Outcome of a pulmonary metastasectomy for an orthopedic malignancy</atitle><jtitle>General thoracic and cardiovascular surgery</jtitle><addtitle>Jpn J Thorac Cardiovasc Surg</addtitle><date>2005-08-01</date><risdate>2005</risdate><volume>53</volume><issue>8</issue><spage>420</spage><epage>425</epage><pages>420-425</pages><issn>1344-4964</issn><issn>1863-6705</issn><eissn>1863-2092</eissn><eissn>1863-6713</eissn><abstract>The purpose of this study was to examine the pulmonary metastatic results in patients with orthopedic malignancies.
Forty-three consecutive patients who underwent a resection of a pulmonary metastasis from an orthopedic malignancy in our hospital were retrospectively investigated. The survival following the resection of a pulmonary metastatic tumor was then analyzed using the Kaplan-Meier method. The impact of clinicopathologic variables on the prognosis including gender, patient age, primary tumor type, the number of the pulmonary metastases, the number of metastasectomies, the operation-era, and the disease-free interval was examined by the Logrank test and Cox's proportional hazards model.
The 5-year overall survivals after a pulmonary metastasectomy were 20.7%. A univariate analysis revealed a significant benefit in the post-metastasectomy survival based on the patients age and the disease-free interval. A multivariate analysis demonstrated patient age to be an independent factor for the prognosis with a hazard ratio of 4.873 (p = 0.0373). When only young (less than 40 years of age) patients were investigated, the histologic type was revealed to be related to the prognosis (p = 0.0004).
Pulmonary metastasis from soft tissue tumors is considered to lead to a poor prognosis for younger patients and a metastasectomy for such patients should be considered as one of the potentially effective treatments.</abstract><cop>Japan</cop><pub>Springer Nature B.V</pub><pmid>16164253</pmid><doi>10.1007/s11748-005-0077-8</doi><tpages>6</tpages></addata></record> |
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| subjects | Adolescent Adult Bone Neoplasms - pathology Child Combined Modality Therapy Female Humans Lung cancer Lung Neoplasms - mortality Lung Neoplasms - secondary Lung Neoplasms - surgery Male Medical prognosis Metastasis Middle Aged Orthopedics Patients Pneumonectomy - mortality Retrospective Studies Sarcoma - mortality Sarcoma - secondary Sarcoma - surgery Survival Analysis Treatment Outcome |
| title | Outcome of a pulmonary metastasectomy for an orthopedic malignancy |
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