Synthesis of N11-anchoring biotinylated artemisinin derivatives and their preliminary biological assessment

Unique endoperoxide moiety of artemisinin and its derivatives has been considered the functionality exhibiting highly potent antimalarial and anticancer activities. To investigate the mechanisms of their biological actions, development of suitable molecular probes including biotinylated derivatives...

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Veröffentlicht in:	Science China Chemistry 2010, Vol.53 (1), p.119-124
Hauptverfasser:	Pan, QiYu, Wang, ShaoZhong, Lu, JinJian, Meng, LingHua, Yao, ZhuJun
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer properties Chemistry Chemistry and Materials Science Chemistry/Food Science Synthesis
Online-Zugang:	Volltext
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