The synthesis of benzoxaboroles and their applications in medicinal chemistry
Benzoxaborole, as a versatile scaffold, plays important roles in organic synthesis, molecular recognition and supramolecular chemistry. It is also a privileged structure in medicinal chemistry due to its desirable physicochemical and drug-like properties. Recently, benzoxaboroles were widely applied...
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| Veröffentlicht in: | Science China. Chemistry 2013-10, Vol.56 (10), p.1372-1381 |
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| container_end_page | 1381 |
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| container_title | Science China. Chemistry |
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| creator | Zhang, Jiong Zhu, MingYan Lin, YiNan Zhou, HuChen |
| description | Benzoxaborole, as a versatile scaffold, plays important roles in organic synthesis, molecular recognition and supramolecular chemistry. It is also a privileged structure in medicinal chemistry due to its desirable physicochemical and drug-like properties. Recently, benzoxaboroles were widely applied as antifungal, antibacterial, antiviral, anti-parasite, and anti-inflammatory agents. This review covers the properties, synthetic methods and applications of benzoxaboroles in medicinal chemistry. |
| doi_str_mv | 10.1007/s11426-013-4981-y |
| format | Article |
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| ispartof | Science China. Chemistry, 2013-10, Vol.56 (10), p.1372-1381 |
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| language | eng |
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| source | Springer Nature - Complete Springer Journals; Alma/SFX Local Collection; ProQuest Central |
| subjects | Chemical synthesis Chemistry Chemistry and Materials Science Chemistry/Food Science Fungicides Reviews 分子识别 合成方法 应用 抗寄生虫 有机合成 物理化学 药物化学 超分子化学 |
| title | The synthesis of benzoxaboroles and their applications in medicinal chemistry |
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