Hydrogen-bonding directed cocrystallization of flexible piperazine with hydroxybenzoic acid derivatives： Structural diversity and synthon prediction

Four hydroxybenzoic acid building blocks, m-hydroxybenzoic acid, 2,4-dihydroxybenzoic acid, 2,5-dihydroxyterephthalic acid, and 5-hydroxyisophthalic acid, have been synthesized as robust cocrystallizing agents and employed in reactions with piperazine, including [（C4H12N2 2＋）.（C7H5O3-）2] （l）, [（CaH1...

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Veröffentlicht in:	Science China. Chemistry 2012-07, Vol.55 (7), p.1228-1235
Hauptverfasser:	Wang, Lei, Xue, RuiFeng, Xu, LingYan, Lu, XiFeng, Chen, RuiXin, Tao, XuTang
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Chemistry and Materials Science Chemistry/Food Science Dihydroxybenzoic acid Hydrogen bonding Single crystals Thermal stability X-射线衍射分析 二羟基苯甲酸 共晶结构 合成子 多样性 氢键 生物灵 羟基酸
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