Inhibition of Quorum Sensing, Motility and Biofilm Formation of Pseudomonas aeruginosa by Copper Oxide Nanostructures
Quorum sensing (QS) is the communication between bacterial cells governed by their population density and regulated by the genes controlling virulence factors and biofilm formation. Multiple mechanisms of biofilms are resistive to antimicrobial chemotherapy; therefore novel strategies are required t...
Gespeichert in:
| Veröffentlicht in: | Journal of cluster science 2021-11, Vol.32 (6), p.1531-1541 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1541 |
|---|---|
| container_issue | 6 |
| container_start_page | 1531 |
| container_title | Journal of cluster science |
| container_volume | 32 |
| creator | Desai, Dnyanada G. Swarali, H. Navale, Govinda R. Prabhune, A. Late, Dattatray J. Dharne, Mahesh S. Walke, Pravin S. |
| description | Quorum sensing (QS) is the communication between bacterial cells governed by their population density and regulated by the genes controlling virulence factors and biofilm formation. Multiple mechanisms of biofilms are resistive to antimicrobial chemotherapy; therefore novel strategies are required to overcome its limitations. Here, we report the effect of various copper oxide nanostructures (CuO-NSs) on quorum sensing inhibition. The two-dimensional CuO-NSs such as interlaced nanodiscs, nanodiscs and leaf-shaped nanosheets are prepared via a simple chemical method. The Quorum sensing inhibition (QSI) activity of all the CuO-NS are examined using reporter strain
Chromobacterium violaceum
CV026 and
Escherichia coli
pSB1142. We found that the CuO-interlaced nanodisc structures exhibit better QSI activity than nanodiscs and leaf-shaped sheets. The interlaced nanodisc structures are inhibited various long-chain
N
-acyl homoserine lactones (AHLs) mediated QS individually and confirmed by other QS-associated phenomena for
Pseudomonas aeruginosa
, including biofilm inhibition, inhibition of virulence factors such as pyocyanin, protease production and swarming motility. Thus QSI activity of CuO-NSs is solely dependent on specific shape offering large surface area and more active sites. The CuO-NS is effective quorum sensing inhibitors, which has potential clinical applications in the management of
P. aeruginosa
associated infections. |
| doi_str_mv | 10.1007/s10876-020-01916-2 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2918293204</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2918293204</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2342-32b548eb95e8dd87ccad5d6bc78f6fd5bda7674de91c598fd7afe259749ce9063</originalsourceid><addsrcrecordid>eNp9kM1KAzEURoMoWKsv4Crg1tEk85NkqcVqoVpFXYdMkqkpnWRMJmDf3tFR3Lm6l8t3vgsHgFOMLjBC9DJixGiVIYIyhDmuMrIHJrikJGOsIvvDjgqUUULZITiKcYMQ4izPJyAt3JutbW-9g76BT8mH1MJn46J163N473u7tf0OSqfhtfWN3bZw7kMrf4nHaJL2rXcyQmlCWlvno4T1Ds5815kAVx9WG_ggh3MfkupTMPEYHDRyG83Jz5yC1_nNy-wuW65uF7OrZaZIXpAsJ3VZMFPz0jCtGVVK6lJXtaKsqRpd1lrSihbacKxKzhpNZWNIyWnBleGoyqfgbOztgn9PJvZi41Nww0tBOGaE5wQVQ4qMKRV8jME0ogu2lWEnMBJfesWoVwx6xbdeQQYoH6E4hN3ahL_qf6hPf1B_4g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2918293204</pqid></control><display><type>article</type><title>Inhibition of Quorum Sensing, Motility and Biofilm Formation of Pseudomonas aeruginosa by Copper Oxide Nanostructures</title><source>ProQuest Central Essentials</source><source>ProQuest Central (Alumni Edition)</source><source>ProQuest Central Student</source><source>ProQuest Central Korea</source><source>ProQuest Central UK/Ireland</source><source>SpringerLink Journals - AutoHoldings</source><source>ProQuest Central</source><creator>Desai, Dnyanada G. ; Swarali, H. ; Navale, Govinda R. ; Prabhune, A. ; Late, Dattatray J. ; Dharne, Mahesh S. ; Walke, Pravin S.</creator><creatorcontrib>Desai, Dnyanada G. ; Swarali, H. ; Navale, Govinda R. ; Prabhune, A. ; Late, Dattatray J. ; Dharne, Mahesh S. ; Walke, Pravin S.</creatorcontrib><description>Quorum sensing (QS) is the communication between bacterial cells governed by their population density and regulated by the genes controlling virulence factors and biofilm formation. Multiple mechanisms of biofilms are resistive to antimicrobial chemotherapy; therefore novel strategies are required to overcome its limitations. Here, we report the effect of various copper oxide nanostructures (CuO-NSs) on quorum sensing inhibition. The two-dimensional CuO-NSs such as interlaced nanodiscs, nanodiscs and leaf-shaped nanosheets are prepared via a simple chemical method. The Quorum sensing inhibition (QSI) activity of all the CuO-NS are examined using reporter strain
Chromobacterium violaceum
CV026 and
Escherichia coli
pSB1142. We found that the CuO-interlaced nanodisc structures exhibit better QSI activity than nanodiscs and leaf-shaped sheets. The interlaced nanodisc structures are inhibited various long-chain
N
-acyl homoserine lactones (AHLs) mediated QS individually and confirmed by other QS-associated phenomena for
Pseudomonas aeruginosa
, including biofilm inhibition, inhibition of virulence factors such as pyocyanin, protease production and swarming motility. Thus QSI activity of CuO-NSs is solely dependent on specific shape offering large surface area and more active sites. The CuO-NS is effective quorum sensing inhibitors, which has potential clinical applications in the management of
P. aeruginosa
associated infections.</description><identifier>ISSN: 1040-7278</identifier><identifier>EISSN: 1572-8862</identifier><identifier>DOI: 10.1007/s10876-020-01916-2</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Antibiotics ; Antimicrobial agents ; Bacteria ; Biofilms ; Biosensors ; Catalysis ; Caustic soda ; Chemistry ; Chemistry and Materials Science ; Copper ; Copper oxides ; Drug resistance ; E coli ; Ethanol ; Inorganic Chemistry ; Lactones ; Metal oxides ; Motility ; Nanochemistry ; Nanomaterials ; Nanoparticles ; Nanostructure ; Nanotechnology ; Nitrates ; Original Paper ; Physical Chemistry ; Physical properties ; Population density ; Pseudomonas aeruginosa ; Scanning electron microscopy ; Swarming ; Virulence</subject><ispartof>Journal of cluster science, 2021-11, Vol.32 (6), p.1531-1541</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2020</rights><rights>Springer Science+Business Media, LLC, part of Springer Nature 2020.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2342-32b548eb95e8dd87ccad5d6bc78f6fd5bda7674de91c598fd7afe259749ce9063</citedby><cites>FETCH-LOGICAL-c2342-32b548eb95e8dd87ccad5d6bc78f6fd5bda7674de91c598fd7afe259749ce9063</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10876-020-01916-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2918293204?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,777,781,21369,21370,21371,21372,23237,27905,27906,33511,33684,33725,33986,34295,41469,42538,43640,43768,43786,43934,44048,51300,64364,64368,72218</link.rule.ids></links><search><creatorcontrib>Desai, Dnyanada G.</creatorcontrib><creatorcontrib>Swarali, H.</creatorcontrib><creatorcontrib>Navale, Govinda R.</creatorcontrib><creatorcontrib>Prabhune, A.</creatorcontrib><creatorcontrib>Late, Dattatray J.</creatorcontrib><creatorcontrib>Dharne, Mahesh S.</creatorcontrib><creatorcontrib>Walke, Pravin S.</creatorcontrib><title>Inhibition of Quorum Sensing, Motility and Biofilm Formation of Pseudomonas aeruginosa by Copper Oxide Nanostructures</title><title>Journal of cluster science</title><addtitle>J Clust Sci</addtitle><description>Quorum sensing (QS) is the communication between bacterial cells governed by their population density and regulated by the genes controlling virulence factors and biofilm formation. Multiple mechanisms of biofilms are resistive to antimicrobial chemotherapy; therefore novel strategies are required to overcome its limitations. Here, we report the effect of various copper oxide nanostructures (CuO-NSs) on quorum sensing inhibition. The two-dimensional CuO-NSs such as interlaced nanodiscs, nanodiscs and leaf-shaped nanosheets are prepared via a simple chemical method. The Quorum sensing inhibition (QSI) activity of all the CuO-NS are examined using reporter strain
Chromobacterium violaceum
CV026 and
Escherichia coli
pSB1142. We found that the CuO-interlaced nanodisc structures exhibit better QSI activity than nanodiscs and leaf-shaped sheets. The interlaced nanodisc structures are inhibited various long-chain
N
-acyl homoserine lactones (AHLs) mediated QS individually and confirmed by other QS-associated phenomena for
Pseudomonas aeruginosa
, including biofilm inhibition, inhibition of virulence factors such as pyocyanin, protease production and swarming motility. Thus QSI activity of CuO-NSs is solely dependent on specific shape offering large surface area and more active sites. The CuO-NS is effective quorum sensing inhibitors, which has potential clinical applications in the management of
P. aeruginosa
associated infections.</description><subject>Antibiotics</subject><subject>Antimicrobial agents</subject><subject>Bacteria</subject><subject>Biofilms</subject><subject>Biosensors</subject><subject>Catalysis</subject><subject>Caustic soda</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Copper</subject><subject>Copper oxides</subject><subject>Drug resistance</subject><subject>E coli</subject><subject>Ethanol</subject><subject>Inorganic Chemistry</subject><subject>Lactones</subject><subject>Metal oxides</subject><subject>Motility</subject><subject>Nanochemistry</subject><subject>Nanomaterials</subject><subject>Nanoparticles</subject><subject>Nanostructure</subject><subject>Nanotechnology</subject><subject>Nitrates</subject><subject>Original Paper</subject><subject>Physical Chemistry</subject><subject>Physical properties</subject><subject>Population density</subject><subject>Pseudomonas aeruginosa</subject><subject>Scanning electron microscopy</subject><subject>Swarming</subject><subject>Virulence</subject><issn>1040-7278</issn><issn>1572-8862</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kM1KAzEURoMoWKsv4Crg1tEk85NkqcVqoVpFXYdMkqkpnWRMJmDf3tFR3Lm6l8t3vgsHgFOMLjBC9DJixGiVIYIyhDmuMrIHJrikJGOsIvvDjgqUUULZITiKcYMQ4izPJyAt3JutbW-9g76BT8mH1MJn46J163N473u7tf0OSqfhtfWN3bZw7kMrf4nHaJL2rXcyQmlCWlvno4T1Ds5815kAVx9WG_ggh3MfkupTMPEYHDRyG83Jz5yC1_nNy-wuW65uF7OrZaZIXpAsJ3VZMFPz0jCtGVVK6lJXtaKsqRpd1lrSihbacKxKzhpNZWNIyWnBleGoyqfgbOztgn9PJvZi41Nww0tBOGaE5wQVQ4qMKRV8jME0ogu2lWEnMBJfesWoVwx6xbdeQQYoH6E4hN3ahL_qf6hPf1B_4g</recordid><startdate>20211101</startdate><enddate>20211101</enddate><creator>Desai, Dnyanada G.</creator><creator>Swarali, H.</creator><creator>Navale, Govinda R.</creator><creator>Prabhune, A.</creator><creator>Late, Dattatray J.</creator><creator>Dharne, Mahesh S.</creator><creator>Walke, Pravin S.</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7XB</scope><scope>88I</scope><scope>8FE</scope><scope>8FG</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>KB.</scope><scope>M2P</scope><scope>P5Z</scope><scope>P62</scope><scope>PDBOC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope></search><sort><creationdate>20211101</creationdate><title>Inhibition of Quorum Sensing, Motility and Biofilm Formation of Pseudomonas aeruginosa by Copper Oxide Nanostructures</title><author>Desai, Dnyanada G. ; Swarali, H. ; Navale, Govinda R. ; Prabhune, A. ; Late, Dattatray J. ; Dharne, Mahesh S. ; Walke, Pravin S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2342-32b548eb95e8dd87ccad5d6bc78f6fd5bda7674de91c598fd7afe259749ce9063</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Antibiotics</topic><topic>Antimicrobial agents</topic><topic>Bacteria</topic><topic>Biofilms</topic><topic>Biosensors</topic><topic>Catalysis</topic><topic>Caustic soda</topic><topic>Chemistry</topic><topic>Chemistry and Materials Science</topic><topic>Copper</topic><topic>Copper oxides</topic><topic>Drug resistance</topic><topic>E coli</topic><topic>Ethanol</topic><topic>Inorganic Chemistry</topic><topic>Lactones</topic><topic>Metal oxides</topic><topic>Motility</topic><topic>Nanochemistry</topic><topic>Nanomaterials</topic><topic>Nanoparticles</topic><topic>Nanostructure</topic><topic>Nanotechnology</topic><topic>Nitrates</topic><topic>Original Paper</topic><topic>Physical Chemistry</topic><topic>Physical properties</topic><topic>Population density</topic><topic>Pseudomonas aeruginosa</topic><topic>Scanning electron microscopy</topic><topic>Swarming</topic><topic>Virulence</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Desai, Dnyanada G.</creatorcontrib><creatorcontrib>Swarali, H.</creatorcontrib><creatorcontrib>Navale, Govinda R.</creatorcontrib><creatorcontrib>Prabhune, A.</creatorcontrib><creatorcontrib>Late, Dattatray J.</creatorcontrib><creatorcontrib>Dharne, Mahesh S.</creatorcontrib><creatorcontrib>Walke, Pravin S.</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>Materials Science Database</collection><collection>Science Database</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Materials Science Collection</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><jtitle>Journal of cluster science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Desai, Dnyanada G.</au><au>Swarali, H.</au><au>Navale, Govinda R.</au><au>Prabhune, A.</au><au>Late, Dattatray J.</au><au>Dharne, Mahesh S.</au><au>Walke, Pravin S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Inhibition of Quorum Sensing, Motility and Biofilm Formation of Pseudomonas aeruginosa by Copper Oxide Nanostructures</atitle><jtitle>Journal of cluster science</jtitle><stitle>J Clust Sci</stitle><date>2021-11-01</date><risdate>2021</risdate><volume>32</volume><issue>6</issue><spage>1531</spage><epage>1541</epage><pages>1531-1541</pages><issn>1040-7278</issn><eissn>1572-8862</eissn><abstract>Quorum sensing (QS) is the communication between bacterial cells governed by their population density and regulated by the genes controlling virulence factors and biofilm formation. Multiple mechanisms of biofilms are resistive to antimicrobial chemotherapy; therefore novel strategies are required to overcome its limitations. Here, we report the effect of various copper oxide nanostructures (CuO-NSs) on quorum sensing inhibition. The two-dimensional CuO-NSs such as interlaced nanodiscs, nanodiscs and leaf-shaped nanosheets are prepared via a simple chemical method. The Quorum sensing inhibition (QSI) activity of all the CuO-NS are examined using reporter strain
Chromobacterium violaceum
CV026 and
Escherichia coli
pSB1142. We found that the CuO-interlaced nanodisc structures exhibit better QSI activity than nanodiscs and leaf-shaped sheets. The interlaced nanodisc structures are inhibited various long-chain
N
-acyl homoserine lactones (AHLs) mediated QS individually and confirmed by other QS-associated phenomena for
Pseudomonas aeruginosa
, including biofilm inhibition, inhibition of virulence factors such as pyocyanin, protease production and swarming motility. Thus QSI activity of CuO-NSs is solely dependent on specific shape offering large surface area and more active sites. The CuO-NS is effective quorum sensing inhibitors, which has potential clinical applications in the management of
P. aeruginosa
associated infections.</abstract><cop>New York</cop><pub>Springer US</pub><doi>10.1007/s10876-020-01916-2</doi><tpages>11</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1040-7278 |
| ispartof | Journal of cluster science, 2021-11, Vol.32 (6), p.1531-1541 |
| issn | 1040-7278 1572-8862 |
| language | eng |
| recordid | cdi_proquest_journals_2918293204 |
| source | ProQuest Central Essentials; ProQuest Central (Alumni Edition); ProQuest Central Student; ProQuest Central Korea; ProQuest Central UK/Ireland; SpringerLink Journals - AutoHoldings; ProQuest Central |
| subjects | Antibiotics Antimicrobial agents Bacteria Biofilms Biosensors Catalysis Caustic soda Chemistry Chemistry and Materials Science Copper Copper oxides Drug resistance E coli Ethanol Inorganic Chemistry Lactones Metal oxides Motility Nanochemistry Nanomaterials Nanoparticles Nanostructure Nanotechnology Nitrates Original Paper Physical Chemistry Physical properties Population density Pseudomonas aeruginosa Scanning electron microscopy Swarming Virulence |
| title | Inhibition of Quorum Sensing, Motility and Biofilm Formation of Pseudomonas aeruginosa by Copper Oxide Nanostructures |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-18T11%3A35%3A18IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Inhibition%20of%20Quorum%20Sensing,%20Motility%20and%20Biofilm%20Formation%20of%20Pseudomonas%20aeruginosa%20by%20Copper%20Oxide%20Nanostructures&rft.jtitle=Journal%20of%20cluster%20science&rft.au=Desai,%20Dnyanada%20G.&rft.date=2021-11-01&rft.volume=32&rft.issue=6&rft.spage=1531&rft.epage=1541&rft.pages=1531-1541&rft.issn=1040-7278&rft.eissn=1572-8862&rft_id=info:doi/10.1007/s10876-020-01916-2&rft_dat=%3Cproquest_cross%3E2918293204%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2918293204&rft_id=info:pmid/&rfr_iscdi=true |