A novel method to prepare three-component hydrogels as neural tissue engineering

Cellulosic nanofibers (CNFs) from Catha Edulis, Arabic Gum, and poly(vinyl alcohol) were blended to prepare novel nebulizing porous nanocomposites films (NCFs). Glutaraldehyde (GLA) was used as a crosslinker. These porous films were characterized by using FTIR, SEM, and DSC. The effects of various factors, such as CNFs concentration, and pH of the medium, on the swelling behavior of NCFs were estimated. The behavior of nebulizing films were tested as well as their possible antimicrobial activities against pathogenic bacteria like C. Albicans (fungus), B. subtilis (G+Ve), S. aureus (G+Ve), P. Vulgaris (G−Ve), and E. Carotovora (G−Ve).