Gd-EOB-DTPA T1 Mapping with Extracellular Volume Fraction in Staging Liver Fibrosis: A Preclinical Investigation

To investigate the value of Gd-EOB-DTPA-enhanced T1 mapping with the extracellular volume (ECV) fraction in diagnosing and staging liver fibrosis (LF) in a CCl 4 -induced rabbit model. Eighty New Zealand white rabbits were injected with CCl 4 50% oil solution to establish an LF model, and 20 rabbits...

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Veröffentlicht in:	Applied magnetic resonance 2021-06, Vol.52 (6), p.677-689
Hauptverfasser:	Wang, Qing, Sheng, Ye, Du, YaNan, Liu, HaiFeng, Zhu, ZuHui, Li, YuFeng, Zhang, JiLei, Xing, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Atoms and Molecules in Strong Fields Biomarkers Biopsy Carbon tetrachloride Correlation coefficients Error analysis Extracellular matrix Fibrosis Gadolinium Laser Matter Interaction Liver Liver cirrhosis Liver diseases Mapping Mathematical models Organic Chemistry Original Paper Parameters Physical Chemistry Physics Physics and Astronomy Rabbits Software Solid State Physics Spectroscopy/Spectrometry Variance analysis
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