Region-Specific Susceptibilities to Cuprizone-Induced Demyelination of C57BL/6 Mouse: In vivo T2WI and DTI Studies at 7.0T

The cuprizone (CPZ) mouse model of demyelination was recognized and used to explore multiple sclerosis (MS)-like brain lesions. In this study, we assessed CPZ-treated mice using T 2 -weighted imaging and diffusion tensor imaging (DTI). C57BL/6 mice treated with 2 weeks of 0.2 % CPZ-containing diet (...

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