Fabrication of hesperidin self-micro-emulsifying nutraceutical delivery system embedded in sodium alginate beads to elicit gastric stability

Poor bioavailability of hesperidin (HES) due to its gastric instability and low aqueous solubility limits its clinical application. The objective of presented work was to incorporate self-microemulsifying drug delivery system of HES (SMEDDS-HES) into alginate beads. The alginate beads were character...

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Veröffentlicht in:	Polymer bulletin (Berlin, Germany) Germany), 2022, Vol.79 (1), p.605-626
Hauptverfasser:	Dangre, Pankaj V., Dusad, Poorva P., Singh, Alok D., Surana, Sanjay J., Chaturvedi, Kaushalendra K., Chalikwar, Shailesh S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antidiabetics Aspect ratio Bioavailability Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Complex Fluids and Microfluidics Drug delivery systems Encapsulation Entrapment Fourier transforms Functional foods & nutraceuticals Microscopy Morphology Organic Chemistry Original Paper Particle size Permeability Physical Chemistry Polymer Sciences Shelf life Sodium Sodium alginate Soft and Granular Matter Stability Surfactants
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