Formulation and evaluation of interpenetrating network of xanthan gum and polyvinylpyrrolidone as a hydrophilic matrix for controlled drug delivery system

The prime objective of the present study was to develop novel colon targeting xanthan gum/polyvinylpyrrolidone-co-poly acrylic acid hydrogels for controlled delivery of 5-fluorouracil at colon-specific site by combining the properties of natural and synthetic polymers. Xanthan gum (XG) and polyvinyl...

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Veröffentlicht in:	Polymer bulletin (Berlin, Germany) Germany), 2021, Vol.78 (1), p.59-80
Hauptverfasser:	Anwar, Maryam, Pervaiz, Fahad, Shoukat, Hina, Noreen, Sobia, Shabbir, Kanwal, Majeed, Asma, Ijaz, Saba
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Acrylic acid Biocompatibility Characterization and Evaluation of Materials Chemical bonds Chemistry Chemistry and Materials Science Colon Colorectal cancer Complex Fluids and Microfluidics Controlled release Crosslinking Drug delivery systems Ethylene glycol Free radical polymerization Free radicals Glycol dimethacrylates Hydrogels Interpenetrating networks Mechanical properties Molecular weight Monomers Organic Chemistry Original Paper Physical Chemistry Polymer Sciences Polymerization Polymers Polyvinylpyrrolidone Soft and Granular Matter Sol-gel processes Structural analysis Swelling Toxicity Xanthan
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