Molecular Model of Norfloxacin Translocation through Yersinia pseudotuberculosis Porin OmpF Channel: Electrophysiological and Molecular Modeling Study

— The interaction of the Yersinia pseudotuberculosis porin OmpF (YpOmpF) with the fluoroquinolone antibiotic norfloxacin (Nf) and its derivatives (mono- and dihydrochloride) was studied using the bilayer lipid membrane (BLM) method, molecular modeling, and antibacterial activity testing. An asymmetr...

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Veröffentlicht in:	Biochemistry (Moscow). Supplement series A, Membrane and cell biology Membrane and cell biology, 2023-12, Vol.17 (Suppl 1), p.S20-S38
Hauptverfasser:	Chistyulin, D. K., Zelepuga, E. A., Novikov, V. L., Balaneva, N. N., Glazunov, V. P., Chingizova, E. A., Khomenko, V. A., Novikova, O. D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Affinity Antibacterial activity Antibiotics Asymmetry Binding sites Biomedical and Life Sciences Cell Biology Channel pores Constrictions Life Sciences Lipids Localization Membranes Molecular modelling Norfloxacin Permeability Pseudotuberculosis Yersinia pseudotuberculosis
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