Klotho Supplementation Reverses Renal Dysfunction and Interstitial Fibrosis in Remnant Kidney

Abstract Introduction: While recent investigations show that klotho exerts renoprotective actions, it has not been fully addressed whether klotho protein supplementation reverses renal damage. Methods: The impacts of subcutaneous klotho supplementation on rats with subtotal nephrectomy were examined...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Kidney & blood pressure research 2023-01, Vol.48 (1), p.326-337
Hauptverfasser:	Takenaka, Tsuneo, Hasan, Arif, Marumo, Takeshi, Inoue, Tsutomu, Miyazaki, Takashi, Suzuki, Hiromichi, Kurosaki, Yoshifumi, Ishii, Naohito, Nishiyama, Akira, Hayashi, Matsuhiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Albuminuria - metabolism Angiotensin Angiotensin II Animals Antibiotics Apoptosis Blood pressure Bone morphogenetic proteins Collagen (type I) Dietary Supplements Enzyme-linked immunosorbent assay Enzymes Excretion Fibroblast growth factor 23 Fibroblasts Fibrosis Glomerular filtration rate Growth factors Histology Impact damage In vivo methods and tests Insulin-like growth factors Kidney - pathology Kidney diseases Kidney Diseases - pathology Kidneys Klotho protein Klotho Proteins - therapeutic use Nephrectomy Phosphates - metabolism Proteins Radioimmunoassay Rats Renal function Renin Research Article Superoxide dismutase Supplements Transforming growth factor-b Urine Veins & arteries
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!