6 Pulse Pressure and APOE ε4 Dose Interact to Affect Cerebral Blood Flow in Older Adults Without Dementia

Objective:Alterations in cerebral blood flow (CBF) are associated with risk of cognitive decline and Alzheimer’s disease (AD). Although apolipoprotein E (APOE) ε4 and greater vascular risk burden have both been linked to reduced CBF in older adults, less is known about how APOE ε4 status and vascula...

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Veröffentlicht in:	Journal of the International Neuropsychological Society 2023-11, Vol.29 (s1), p.107-108
Hauptverfasser:	Edwards, Lauren, Thomas, Kelsey R, Weigand, Alexandra J, Edmonds, Emily C, Clark, Alexandra L, Brenner, Einat K, Nation, Daniel A, Delano-Wood, Lisa, Bondi, Mark W, Bangen, Katherine J
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Alzheimer's disease Amyloid Antihypertensives Apolipoprotein E Apolipoprotein E4 Blood flow Blood pressure Cerebral blood flow Cholesterol Cognitive ability Cortex (entorhinal) Cortex (frontal) Cortex (parietal) Dementia Dementia disorders Diabetes mellitus Frontal gyrus Genotypes Genotyping Hippocampus Ischemia Neurodegenerative diseases Neuroimaging Older people Positron emission tomography Poster Session 01: Medical \| Neurological Disorders \| Neuropsychiatry \| Psychopharmacology Spin labeling Temporal lobe
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