Inhibition of ubiquitin specific peptidase 14 (USP14) promotes ER-phagy by inducing ER stress in human hepatoma HepG2 cells

Autophagy plays a critical role in regulating the quality and quantity of cellular compartments; however, the mechanisms governing endoplasmic reticulum (ER) autophagy (ER-phagy) are still largely undefined. In this study, we identified several inhibitors of USP14, a ubiquitin-specific protease, inc...

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Veröffentlicht in:	Animal cells and systems 2023, 27(1), , pp.394-402
Hauptverfasser:	Kim, Joon Bum, Bae, Ji-Eun, Park, Na Yeon, Jo, Doo Sin, Kim, Yong Hwan, Jeong, Kwiwan, Kim, Pansoo, Lee, Won-Ha, Yeom, Eunbyul, Cho, Dong-Hyung
Format:	Artikel
Sprache:	eng
Schlagworte:	Autophagy b-AP15 Cell activation Endoplasmic reticulum ER stress ER-phagy Hepatoma IU1 Kinases Tauroursodeoxycholic acid Ubiquitin-specific proteinase USP14 생물학
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