STUDIES ON ANTI-OBESITY ACTIVITY OF METHANOLIC EXTRACT OF GARDENIA RESINIFERA ROTH IN TRITON X-100 INDUCED OBESITY
In the current study, we wanted to evaluate Gardenia resinifera potential to prevent obesity in Triton X-100 induced rats. The efficiency of the common anti-obesity drug atorvastasin (10 mg/kg b.wt.) was compared to that of the methanolic extract of Gardenia resinifera (MEGR), which was synthesized...
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| Veröffentlicht in: | NeuroQuantology 2022-01, Vol.20 (10), p.1590 |
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| creator | Chougule, P K Ghaisas, M M Shete, R V |
| description | In the current study, we wanted to evaluate Gardenia resinifera potential to prevent obesity in Triton X-100 induced rats. The efficiency of the common anti-obesity drug atorvastasin (10 mg/kg b.wt.) was compared to that of the methanolic extract of Gardenia resinifera (MEGR), which was synthesized and tested at different doses (50 mg/kg, 100 mg/kg,). The serum levels of total cholesterol (TC), triglycerides (TG), low-density lipoproteins (LDL), and very low-density lipoproteins (VLDL) all significantly (P 0.05) dropped when MEGR was administered along with Triton X-100, but high-density lipoproteins (HDL) rise. We demonstrate that MEGR has potential anti-obesity activity based on our findings. |
| doi_str_mv | 10.14704/nq.2022.20.10.NQ55124 |
| format | Article |
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| subjects | Body fat Cholesterol Constipation Density Flavonoids Health care High density lipoprotein Hyperlipidemia Leaves Lipids Lipoproteins Liver Obesity Pharmacology Pharmacy Phytochemicals Statistical analysis Toxicity Triglycerides Variance analysis |
| title | STUDIES ON ANTI-OBESITY ACTIVITY OF METHANOLIC EXTRACT OF GARDENIA RESINIFERA ROTH IN TRITON X-100 INDUCED OBESITY |
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