ANTI-INFLAMMATORY ACTIVITY OF HYDROALCOHOLIC EXTRACT OF IPOMOEA CARNEA
The objective of present study was to evaluate the anti-inflammatory activity of alcoholic extracts of Ipomoea carnea leaves. Inflammatory diseases including different types of rheumatic diseases are very common throughout the world. Therefore, the search for a better tolerated anti-inflammatory age...
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| Veröffentlicht in: | NeuroQuantology 2022-01, Vol.20 (10), p.1490 |
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| creator | Mani, Munesh Thakkar, Navneet Kumar, Prevesh Verma, Navneet Shukla, Divaker |
| description | The objective of present study was to evaluate the anti-inflammatory activity of alcoholic extracts of Ipomoea carnea leaves. Inflammatory diseases including different types of rheumatic diseases are very common throughout the world. Therefore, the search for a better tolerated anti-inflammatory agent appears to be a necessity. Ipomoea carnea is used for the treatment of skin diseases in India. Anti-inflammatory activity was evaluated using the carrageenan (0.1%) induced rat paw edema method. The mature green leaves of Ipomoea carnea were collected and authenticated. For the screening of anti-inflammatory activity, the extracts were administered orally at a dose of 100 mg/kg, 200mg/kg and 400 mg/kg body weight. The animals were divided into five groups of six animals each. Group 1 served as the the control and group 2 as reference standard (Etoricoxib 6 mg/kg), group 3, 4 and 5 animals were treated with 100mg / kg of, 200 mg/kg and 400 mg/kg alcoholic extract, respectively. Paw volume was significantly (p |
| doi_str_mv | 10.14704/nq.2022.20.10.NQ55113 |
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Inflammatory diseases including different types of rheumatic diseases are very common throughout the world. Therefore, the search for a better tolerated anti-inflammatory agent appears to be a necessity. Ipomoea carnea is used for the treatment of skin diseases in India. Anti-inflammatory activity was evaluated using the carrageenan (0.1%) induced rat paw edema method. The mature green leaves of Ipomoea carnea were collected and authenticated. For the screening of anti-inflammatory activity, the extracts were administered orally at a dose of 100 mg/kg, 200mg/kg and 400 mg/kg body weight. The animals were divided into five groups of six animals each. Group 1 served as the the control and group 2 as reference standard (Etoricoxib 6 mg/kg), group 3, 4 and 5 animals were treated with 100mg / kg of, 200 mg/kg and 400 mg/kg alcoholic extract, respectively. Paw volume was significantly (p<0.01) reduced in test treated groups (400 mg/kg body weight) as compared to control group. 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Inflammatory diseases including different types of rheumatic diseases are very common throughout the world. Therefore, the search for a better tolerated anti-inflammatory agent appears to be a necessity. Ipomoea carnea is used for the treatment of skin diseases in India. Anti-inflammatory activity was evaluated using the carrageenan (0.1%) induced rat paw edema method. The mature green leaves of Ipomoea carnea were collected and authenticated. For the screening of anti-inflammatory activity, the extracts were administered orally at a dose of 100 mg/kg, 200mg/kg and 400 mg/kg body weight. The animals were divided into five groups of six animals each. Group 1 served as the the control and group 2 as reference standard (Etoricoxib 6 mg/kg), group 3, 4 and 5 animals were treated with 100mg / kg of, 200 mg/kg and 400 mg/kg alcoholic extract, respectively. Paw volume was significantly (p<0.01) reduced in test treated groups (400 mg/kg body weight) as compared to control group. 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Inflammatory diseases including different types of rheumatic diseases are very common throughout the world. Therefore, the search for a better tolerated anti-inflammatory agent appears to be a necessity. Ipomoea carnea is used for the treatment of skin diseases in India. Anti-inflammatory activity was evaluated using the carrageenan (0.1%) induced rat paw edema method. The mature green leaves of Ipomoea carnea were collected and authenticated. For the screening of anti-inflammatory activity, the extracts were administered orally at a dose of 100 mg/kg, 200mg/kg and 400 mg/kg body weight. The animals were divided into five groups of six animals each. Group 1 served as the the control and group 2 as reference standard (Etoricoxib 6 mg/kg), group 3, 4 and 5 animals were treated with 100mg / kg of, 200 mg/kg and 400 mg/kg alcoholic extract, respectively. Paw volume was significantly (p<0.01) reduced in test treated groups (400 mg/kg body weight) as compared to control group. The present study revealed that the leaves of the plant Ipomoea carnea possess significant anti-inflammatory activity as evidence in Carrageenan induced paw edema method.</abstract><cop>Bornova Izmir</cop><pub>NeuroQuantology</pub><doi>10.14704/nq.2022.20.10.NQ55113</doi></addata></record> |
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| subjects | Animals Body weight Carrageenan Edema Rheumatic diseases |
| title | ANTI-INFLAMMATORY ACTIVITY OF HYDROALCOHOLIC EXTRACT OF IPOMOEA CARNEA |
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