Exploration of the inhibition action of TPGS on tumor cells and its combined use with chemotherapy drugs

D-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS) is a commonly used nonionic surfactant used as a pharmaceutical carrier in different drug delivery systems. TPGS can reverse P-glycoprotein (P-gp)-mediated multidrug resistance (MDR) and also has anticancer activities. It suggests that whe...

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Veröffentlicht in:	Drug delivery 2023-12, Vol.30 (1), p.2183830-2183830
Hauptverfasser:	Tang, Lan, Huang, Kaijuan, Jiang, Wenhui, Fu, Lulu, Zhang, Ran, Shen, Liting, Ou, Zhimin, Huang, Ye, Zhang, Zhenhai
Format:	Artikel
Sprache:	eng
Schlagworte:	Albumin-Bound Paclitaxel Animals antitumor Apoptosis ATP Binding Cassette Transporter, Subfamily B ATP Binding Cassette Transporter, Subfamily B, Member 1 co-administration D-α-Tocopheryl polyethylene glycol 1000 succinate Drug delivery systems intracellular calcium ion concentration marketed chemotherapeutic agents Mice Mice, Nude
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