Synthesis, Characterization and in vitro Anticancer Evaluation of Novel Quinoline-3- Carboxamide Derivatives as Inhibitors of PDGFR

Cancer cells exploit transmembrane receptor protein kinases like platelet derived growth factor (PDGF) for their survival, which leads to the development of resistance towards anticancer agents. The importance of inhibiting PDGF receptor is well established. In this article, twelve novel substituted...

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