Individualizing Glioma Radiotherapy Planning by Optimization of Data and Physics-Informed Discrete Loss

Brain tumor growth is unique to each glioma patient and extends beyond what is visible in imaging scans, infiltrating surrounding brain tissue. Understanding these hidden patient-specific progressions is essential for effective therapies. Current treatment plans for brain tumors, such as radiotherap...

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Veröffentlicht in:	arXiv.org 2024-04
Hauptverfasser:	Balcerak, Michal, Weidner, Jonas, Karnakov, Petr, Ezhov, Ivan, Litvinov, Sergey, Koumoutsakos, Petros, Zhang, Ray Zirui, Lowengrub, John S, Wiestler, Bene, Menze, Bjoern
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain Brain cancer Constraints Cost function Mathematical analysis Medical imaging Optimization Parameter estimation Partial differential equations Radiation therapy Spatial distribution Tumors
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