Measures of Dosage for Spinal-Cord Electrical Stimulation: Review and Proposal

This manuscript proposes an electrical definition of therapeutic dose for spinal-cord systems used for the treatment of chronic pain, analogous to the pharmacological definition. Dose-response relationships are fundamental to pharmacology, radio-therapy, and other treatments, but have never been pro...

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Veröffentlicht in:	IEEE transactions on neural systems and rehabilitation engineering 2023, Vol.31, p.4653-4660
Hauptverfasser:	Single, Peter S., Scott, Jonathan B., Mugan, Dave
Format:	Artikel
Sprache:	eng
Schlagworte:	Action potentials Chronic Pain Current measurement dose response relationship Dose-response effects Drug therapy Electric Stimulation Electrical stimuli Electrodes evoked action potential evoked compound action potential Evoked Potentials Humans Medical treatment Nerves Nervous tissues Neuromodulation Pain Pharmacology Radiation therapy Sacrum Spinal cord Spinal Cord - physiology spinal cord stimulation Spinal Cord Stimulation - methods Standardization Stimulation Vagus nerve Voltage measurement
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