Nelarabine-induced myelopathy in patients undergoing allogeneic hematopoietic cell transplantation: a report of three cases

Nelarabine is an effective treatment for T-cell acute lymphoblastic leukemia/lymphoma. Myelopathy is a rare but serious adverse event associated with this drug. Three patients who received nelarabine at the National Cancer Center Hospital from December 2014 to March 2021 developed myelopathy 20 days...

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Veröffentlicht in:	International journal of hematology 2023-06, Vol.117 (6), p.933-940
Hauptverfasser:	Fukuta, Takanori, Tanaka, Takashi, Hashimoto, Taiki, Isahaya, Kenji, Kubo, Yuko, Yamano, Yoshihisa, Satomi, Kaishi, Hiraoka, Nobuyoshi, Shirakawa, Nami, Arakawa, Ayumu, Ogawa, Chitose, Nishimura, Nao, Aoki, Jun, Ito, Ayumu, Inamoto, Yoshihiro, Kim, Sung-Won, Fukuda, Takahiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Acute lymphoblastic leukemia Allografts Arabinonucleosides - adverse effects Autopsies Autopsy Case Report Central nervous system diseases Hematology Hematopoietic Stem Cell Transplantation - adverse effects Hematopoietic Stem Cell Transplantation - methods Hematopoietic stem cells Humans Leukemia Lymphatic leukemia Lymphocytes T Lymphoma Magnetic resonance imaging Medicine Medicine & Public Health Medulla oblongata Methylprednisolone Mucormycosis Neurotoxicity Oncology Patients Positron emission Positron emission tomography Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy Spinal cord Spinal Cord Diseases - chemically induced Spinal Cord Diseases - therapy Stem cell transplantation Transplantation
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