Hypotension and Hypoglycaemic Incidence Among End-Stage Renal Disease (ESRD) Patients During Haemodialysis Procedures

Introduction: hypotension and hypoglycaemic are complications that frequently occur in hemodialysis of End Stage Renal Disease (ESRD) patients which can increase mortality. [1-2] The prevalence of intradialytic hypotension was 18 years old, undergoing hemodialysis routine, taking antihypertensive or...

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Veröffentlicht in:Drug safety 2023-11, Vol.46 (11), p.1251-1252
Hauptverfasser: Rahmawati, F, Patria, D C E, Nugraheni, Y N
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creator Rahmawati, F
Patria, D C E
Nugraheni, Y N
description Introduction: hypotension and hypoglycaemic are complications that frequently occur in hemodialysis of End Stage Renal Disease (ESRD) patients which can increase mortality. [1-2] The prevalence of intradialytic hypotension was 18 years old, undergoing hemodialysis routine, taking antihypertensive or/and antidiabetic drugs, and being willing to be interviewed. Adverse effect hypotension if systolic blood pressure after hemodialysis is
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[1-2] The prevalence of intradialytic hypotension was &lt;12% while the incidence of hypoglycemia in patients with chronic renal failure with diabetes who underwent hemodialysis was 52.9%. [3-4] To avoid these side effects, information is needed regarding the appropriate time to use antihypertensive and antidiabetic drugs in patients on the day of hemodialysis. Research on this matter has not been carried out in Indonesia. Aim: This study aims to determine a profile of the time use of antihypertensive and antidiabetic and identify the incidence of hypotension and hypoglycaemic effect in ESRD patients undergoing hemodialysis. Methods: the study used an observational cross-sectional method conducted at Installation Hemodialysis RSUP Dr. Soeradji Tirtonegoro Klaten and Purbalingga Hospital in January to March 2023. Data collection was done prospectively using the accidental sampling method. The samples used in this study were 101 patients who met the inclusion criteria with 225 total hemodialysis sessions. The inclusion criteria were &gt;18 years old, undergoing hemodialysis routine, taking antihypertensive or/and antidiabetic drugs, and being willing to be interviewed. Adverse effect hypotension if systolic blood pressure after hemodialysis is &lt;100 mmHg and hypoglycemia if blood glucose levels after hemodialysis &lt;70 mg/dL. Data analysis was carried out descriptively based on data from medical records and the results of interviews with patients. Results: the results showed that the use of antihypertensive and/or antidiabetic drugs was mostly taken before hemodialysis. Hypotension occurred in two (2 %) patients, while hypoglycemia occurred in one (1%) patient. These patients consume antihypertensive and antidiabetic before the hemodialysis session. Blood pressure decreased after hemodialysis, the mean systolic and diastolic blood pressure in pre and post hemodialysis respectively 157.65 vs 148.84 mmHg and 83.57 vs 81.39 mmHg. The average random blood sugar after hemodialysis is 143.56 mg/dL. Other adverse events mainly detected during hemodialysis were headache, followed by nausea, and muscle cramps. Conclusions: the incidence of hypotension and hypoglycemia is relatively low. Although many factors have contributed to that event, it is necessary to provide appropriate information to patients about the time to use antihypertensives and antidiabetics during hemodialysis to avoid adverse effects.</description><identifier>ISSN: 0114-5916</identifier><identifier>EISSN: 1179-1942</identifier><language>eng</language><publisher>Auckland: Springer Nature B.V</publisher><subject>Antidiabetics ; Antihypertensives ; Blood glucose ; Blood levels ; Blood pressure ; Complications ; Cramps ; Criteria ; Data analysis ; Data collection ; Diabetes mellitus ; Drugs ; End-stage renal disease ; Hemodialysis ; Hypoglycemia ; Hypotension ; Kidney diseases ; Medical records ; Patients ; Renal failure ; Sampling methods ; Side effects ; Time of use</subject><ispartof>Drug safety, 2023-11, Vol.46 (11), p.1251-1252</ispartof><rights>Copyright Springer Nature B.V. Nov 2023</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids></links><search><creatorcontrib>Rahmawati, F</creatorcontrib><creatorcontrib>Patria, D C E</creatorcontrib><creatorcontrib>Nugraheni, Y N</creatorcontrib><title>Hypotension and Hypoglycaemic Incidence Among End-Stage Renal Disease (ESRD) Patients During Haemodialysis Procedures</title><title>Drug safety</title><description>Introduction: hypotension and hypoglycaemic are complications that frequently occur in hemodialysis of End Stage Renal Disease (ESRD) patients which can increase mortality. [1-2] The prevalence of intradialytic hypotension was &lt;12% while the incidence of hypoglycemia in patients with chronic renal failure with diabetes who underwent hemodialysis was 52.9%. [3-4] To avoid these side effects, information is needed regarding the appropriate time to use antihypertensive and antidiabetic drugs in patients on the day of hemodialysis. Research on this matter has not been carried out in Indonesia. Aim: This study aims to determine a profile of the time use of antihypertensive and antidiabetic and identify the incidence of hypotension and hypoglycaemic effect in ESRD patients undergoing hemodialysis. Methods: the study used an observational cross-sectional method conducted at Installation Hemodialysis RSUP Dr. Soeradji Tirtonegoro Klaten and Purbalingga Hospital in January to March 2023. Data collection was done prospectively using the accidental sampling method. The samples used in this study were 101 patients who met the inclusion criteria with 225 total hemodialysis sessions. The inclusion criteria were &gt;18 years old, undergoing hemodialysis routine, taking antihypertensive or/and antidiabetic drugs, and being willing to be interviewed. Adverse effect hypotension if systolic blood pressure after hemodialysis is &lt;100 mmHg and hypoglycemia if blood glucose levels after hemodialysis &lt;70 mg/dL. Data analysis was carried out descriptively based on data from medical records and the results of interviews with patients. Results: the results showed that the use of antihypertensive and/or antidiabetic drugs was mostly taken before hemodialysis. Hypotension occurred in two (2 %) patients, while hypoglycemia occurred in one (1%) patient. These patients consume antihypertensive and antidiabetic before the hemodialysis session. Blood pressure decreased after hemodialysis, the mean systolic and diastolic blood pressure in pre and post hemodialysis respectively 157.65 vs 148.84 mmHg and 83.57 vs 81.39 mmHg. The average random blood sugar after hemodialysis is 143.56 mg/dL. Other adverse events mainly detected during hemodialysis were headache, followed by nausea, and muscle cramps. Conclusions: the incidence of hypotension and hypoglycemia is relatively low. Although many factors have contributed to that event, it is necessary to provide appropriate information to patients about the time to use antihypertensives and antidiabetics during hemodialysis to avoid adverse effects.</description><subject>Antidiabetics</subject><subject>Antihypertensives</subject><subject>Blood glucose</subject><subject>Blood levels</subject><subject>Blood pressure</subject><subject>Complications</subject><subject>Cramps</subject><subject>Criteria</subject><subject>Data analysis</subject><subject>Data collection</subject><subject>Diabetes mellitus</subject><subject>Drugs</subject><subject>End-stage renal disease</subject><subject>Hemodialysis</subject><subject>Hypoglycemia</subject><subject>Hypotension</subject><subject>Kidney diseases</subject><subject>Medical records</subject><subject>Patients</subject><subject>Renal failure</subject><subject>Sampling methods</subject><subject>Side effects</subject><subject>Time of use</subject><issn>0114-5916</issn><issn>1179-1942</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqNjUFqwzAQRUVpoG7SOwx00ywMkuvE9rLULs4uJN0HIU2MgjNKNdLCt68LOUBXjw-P_x5EplTV5Kopi0eRSaXKfNOo7ZN4Zr5IKetiW2ci9dPNRyR2nkCThb89jJPReHUGdmScRTIIH1dPA3Rk82PUA8IBSY_QOkbNCG_d8dCuYa-jQ4oMbQpu1vv5xVunx4kdwz54gzYF5JVYnPXI-HLnUrx-dd-ffX4L_ichx9PFpzAH-FTUjZRVpcr6_X_WLzo_TTA</recordid><startdate>20231101</startdate><enddate>20231101</enddate><creator>Rahmawati, F</creator><creator>Patria, D C E</creator><creator>Nugraheni, Y N</creator><general>Springer Nature B.V</general><scope>3V.</scope><scope>4T-</scope><scope>7RV</scope><scope>7T2</scope><scope>7TK</scope><scope>7U7</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope></search><sort><creationdate>20231101</creationdate><title>Hypotension and Hypoglycaemic Incidence Among End-Stage Renal Disease (ESRD) Patients During Haemodialysis Procedures</title><author>Rahmawati, F ; 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[1-2] The prevalence of intradialytic hypotension was &lt;12% while the incidence of hypoglycemia in patients with chronic renal failure with diabetes who underwent hemodialysis was 52.9%. [3-4] To avoid these side effects, information is needed regarding the appropriate time to use antihypertensive and antidiabetic drugs in patients on the day of hemodialysis. Research on this matter has not been carried out in Indonesia. Aim: This study aims to determine a profile of the time use of antihypertensive and antidiabetic and identify the incidence of hypotension and hypoglycaemic effect in ESRD patients undergoing hemodialysis. Methods: the study used an observational cross-sectional method conducted at Installation Hemodialysis RSUP Dr. Soeradji Tirtonegoro Klaten and Purbalingga Hospital in January to March 2023. Data collection was done prospectively using the accidental sampling method. The samples used in this study were 101 patients who met the inclusion criteria with 225 total hemodialysis sessions. The inclusion criteria were &gt;18 years old, undergoing hemodialysis routine, taking antihypertensive or/and antidiabetic drugs, and being willing to be interviewed. Adverse effect hypotension if systolic blood pressure after hemodialysis is &lt;100 mmHg and hypoglycemia if blood glucose levels after hemodialysis &lt;70 mg/dL. Data analysis was carried out descriptively based on data from medical records and the results of interviews with patients. Results: the results showed that the use of antihypertensive and/or antidiabetic drugs was mostly taken before hemodialysis. Hypotension occurred in two (2 %) patients, while hypoglycemia occurred in one (1%) patient. These patients consume antihypertensive and antidiabetic before the hemodialysis session. Blood pressure decreased after hemodialysis, the mean systolic and diastolic blood pressure in pre and post hemodialysis respectively 157.65 vs 148.84 mmHg and 83.57 vs 81.39 mmHg. The average random blood sugar after hemodialysis is 143.56 mg/dL. Other adverse events mainly detected during hemodialysis were headache, followed by nausea, and muscle cramps. Conclusions: the incidence of hypotension and hypoglycemia is relatively low. Although many factors have contributed to that event, it is necessary to provide appropriate information to patients about the time to use antihypertensives and antidiabetics during hemodialysis to avoid adverse effects.</abstract><cop>Auckland</cop><pub>Springer Nature B.V</pub></addata></record>
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subjects Antidiabetics
Antihypertensives
Blood glucose
Blood levels
Blood pressure
Complications
Cramps
Criteria
Data analysis
Data collection
Diabetes mellitus
Drugs
End-stage renal disease
Hemodialysis
Hypoglycemia
Hypotension
Kidney diseases
Medical records
Patients
Renal failure
Sampling methods
Side effects
Time of use
title Hypotension and Hypoglycaemic Incidence Among End-Stage Renal Disease (ESRD) Patients During Haemodialysis Procedures
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