SARS-CoV-2 infection during pregnancy - single-center retrospective study

The SARS-CoV-2 virus infection has spread to almost all countries in the last two years. Pregnancy complicated with COVID-19 is a unique situation and challenge for doctors. The study aimed to evaluate obstetric results, and biochemical test results and to analyze the treatment used in pregnant pati...

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Veröffentlicht in:Ginekologia polska 2023-01, Vol.94 (10), p.831-838
Hauptverfasser: Skalska-Swistek, Malgorzata, Kolak, Magdalena, Jaworowski, Andrzej P, Swistek, Rafal, Micek, Agnieszka, Huras, Hubert
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container_end_page 838
container_issue 10
container_start_page 831
container_title Ginekologia polska
container_volume 94
creator Skalska-Swistek, Malgorzata
Kolak, Magdalena
Jaworowski, Andrzej P
Swistek, Rafal
Micek, Agnieszka
Huras, Hubert
description The SARS-CoV-2 virus infection has spread to almost all countries in the last two years. Pregnancy complicated with COVID-19 is a unique situation and challenge for doctors. The study aimed to evaluate obstetric results, and biochemical test results and to analyze the treatment used in pregnant patients complicated with COVID-19 infection. A retrospective analysis of 146 pregnant patients hospitalized at the Department of Obstetrics and Perinatology Jagiellonian University Medical College (JUMC) in Krakow was conducted from July 2020 to August 2021. In the analyzed group respiratory failure occurred in 19.19% of cases and intravascular coagulation syndrome (DIC) in 1.37%. One patient died (0.68%). 16.6% of cases were transferred to the Intensive Care Unit (ICU) and required intubation. The remaining cases were mild: 39.04% were asymptomatic, 41.78% reported cough, 30.82% dyspnoea and 23.97% myalgia. In the laboratory tests increased values of CRP and IL-6 were observed with normal levels of leukocytes. Additionally, a decreased level of total protein and an increased level of d-dimers were detected. 98.63% of patients received a prophylactic dose of low molecular weight heparin. 46.58% of cases needed additional antibiotic therapy. Cesarean sections were performed in 59.59% of cases. The children were born in good general condition. Vertical transmission of SARS-CoV-2 to the newborn has not been confirmed. Data from the above study show a significant effect of COVID-19 on pregnant patients. Almost one in five pregnant women occurred respiratory failure and most of them had to be transferred to the ICU department and had to be intubated.
doi_str_mv 10.5603/gpl.95565
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subjects Child
COVID-19
Disease transmission
Female
Humans
Infant, Newborn
Infections
Infectious Disease Transmission, Vertical - prevention & control
Parturition
Pregnancy
Pregnancy Complications, Infectious - diagnosis
Pregnancy Complications, Infectious - drug therapy
Pregnancy Complications, Infectious - epidemiology
Pregnancy Outcome - epidemiology
Respiratory failure
Respiratory Insufficiency
Retrospective Studies
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
title SARS-CoV-2 infection during pregnancy - single-center retrospective study
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