Front Cover: Structure‐Activity Relationships, Tolerability and Efficacy of Microtubule‐Active 1,2,4‐Triazolopyrimidines as Potential Candidates to Treat Human African Trypanosomiasis
The Front Cover shows a microscopy image of mouse blood containing Trypanosoma brucei parasites, one of which (in the box) is magnified, and an example of anti‐trypanosomal microtubule‐stabilizing 1,2,4‐triazolo[1,5‐a]pyrimidines docked within the vinca site of Trypanosoma brucei tubulin. Cover desi...
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| Veröffentlicht in: | ChemMedChem 2023-10, Vol.18 (20) |
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| creator | Monti, Ludovica Liu, Lawrence J Varricchio, Carmine Lucero, Bobby Alle, Thibault Yang, Wenqian Ido Bem‐Shalom Gilson, Michael Brunden, Kurt R Brancale, Andrea Caffrey, Conor R Ballatore, Carlo |
| description | The Front Cover shows a microscopy image of mouse blood containing Trypanosoma brucei parasites, one of which (in the box) is magnified, and an example of anti‐trypanosomal microtubule‐stabilizing 1,2,4‐triazolo[1,5‐a]pyrimidines docked within the vinca site of Trypanosoma brucei tubulin. Cover design by Dr. Ludovica Monti et al. More information can be found in the Research Article by Ludovica Monti, Conor R. Caffrey, Carlo Ballatore et al. |
| doi_str_mv | 10.1002/cmdc.202300558 |
| format | Article |
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| language | eng |
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| source | Wiley Online Library Journals Frontfile Complete |
| subjects | African trypanosomiasis Microscopy Parasites Pyrimidines Trypanosoma brucei Tubulin Vector-borne diseases |
| title | Front Cover: Structure‐Activity Relationships, Tolerability and Efficacy of Microtubule‐Active 1,2,4‐Triazolopyrimidines as Potential Candidates to Treat Human African Trypanosomiasis |
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