Marchiafava-Bignami Disease with Cortical Involvement: A Case Report

Marchiafava-Bignami disease is a rare, chronic alcoholism related disease which characterized with corpus callosum demyelination and necrosis. Marchiafava-Bignami disease typically begins in the body of the corpus callosum and later involves the genu and then splenium. Cortical lesions are rare, and...

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Veröffentlicht in:Boğaziçi tıp dergisi 2023-01, Vol.10 (2), p.117
Hauptverfasser: Buse, Gül Belen, Doğan, Ceyda, Mehmet Güney Şenol, Özdağ, Mehmet Fatih
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creator Buse, Gül Belen
Doğan, Ceyda
Mehmet Güney Şenol
Özdağ, Mehmet Fatih
description Marchiafava-Bignami disease is a rare, chronic alcoholism related disease which characterized with corpus callosum demyelination and necrosis. Marchiafava-Bignami disease typically begins in the body of the corpus callosum and later involves the genu and then splenium. Cortical lesions are rare, and they are known to have a poor prognosis. In our case, we will describe a 46-year-old chronic alcoholic male patient who uses alcohol for 30 years, with unusual cranial MRI findings like cortical involvement and a good prognosis.
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title Marchiafava-Bignami Disease with Cortical Involvement: A Case Report
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