Binding patterns of derivatives of fisetin and chrysin to the enzyme complex cyclin-dependent kinase 6/cyclin D

Clinical inhibitors of cell-cycle regulatory enzyme cyclin-dependent kinase 6 (CDK6) are not free of harmful consequences to human bodies. Flavonoids fisetin and chrysin bestow anti-cancer benefits by inhibiting the activities of CDK6 with strong binding affinities. To understand the structure requi...

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