Development and Validation of a Deep Learning-Based Microsatellite Instability Predictor from Prostate Cancer Whole-Slide Images

Microsatellite instability-high (MSI-H) is a tumor agnostic biomarker for immune checkpoint inhibitor therapy. However, MSI status is not routinely tested in prostate cancer, in part due to low prevalence and assay cost. As such, prediction of MSI status from hematoxylin and eosin (H&E) stained...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	arXiv.org 2023-10
Hauptverfasser:	Hu, Qiyuan, Rizvi, Abbas A, Schau, Geoffery, Ingale, Kshitij, Muller, Yoni, Baits, Rachel, Pretzer, Sebastian, BenTaieb, Aïcha, Gordhamer, Abigail, Nussenzveig, Roberto, Cole, Adam, Leavitt, Matthew O, Joshi, Rohan P, Beaubier, Nike, Stumpe, Martin C, Nagpal, Kunal
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Biomarkers Deep learning Immunotherapy Machine learning Medical imaging Prostate cancer Subgroups
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!