Novel valproate half-sandwich rhodium and iridium conjugates to fight against multidrug-resistant Gram-positive bacteria
New valproate Ir( iii ) and Rh( iii ) half-sandwich conjugates containing a C,N-phenylbenzimidazole chelated ligand have been synthesized and characterized. The valproic acid conjugation to organometallic fragments seems to switch on the antibacterial activity of the complexes towards Enterococcus f...
Gespeichert in:
| Veröffentlicht in: | Dalton transactions : an international journal of inorganic chemistry 2023-10, Vol.52 (38), p.13482-13486 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 13486 |
|---|---|
| container_issue | 38 |
| container_start_page | 13482 |
| container_title | Dalton transactions : an international journal of inorganic chemistry |
| container_volume | 52 |
| creator | Marco, Alicia Vigueras, Gloria Busto, Natalia Cutillas, Natalia Bautista, Delia Ruiz, José |
| description | New valproate Ir(
iii
) and Rh(
iii
) half-sandwich conjugates containing a C,N-phenylbenzimidazole chelated ligand have been synthesized and characterized. The valproic acid conjugation to organometallic fragments seems to switch on the antibacterial activity of the complexes towards
Enterococcus faecium
and
Staphylococcus aureus
Gram-positive bacteria.
The valproic acid conjugation to Ir(
iii
) and Rh(
iii
) half-sandwich complexes seems to switch on their antibacterial activity towards
Enterococcus faecium
and
Staphylococcus aureus
Gram-positive bacteria. |
| doi_str_mv | 10.1039/d3dt01678a |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2871564734</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2871564734</sourcerecordid><originalsourceid>FETCH-LOGICAL-c332t-1d0fa459a3dc08ef61bbf35c7fcbf594084e83b3d200946381be5a025c4081b13</originalsourceid><addsrcrecordid>eNpd0ctrGzEQB2AREuLUzSX3BEEvpbCtXvs6mrhNA6a9JOdlVo-1zO7KkbRO-99HtRMXctKI-Rik-SF0RclXSnj9TXEVCS3KCk7QBRVlmdWMi9NjzYoZ-hDChhDGSM7O0YyXPK-IEBfozy-30z3eQb_1DqLGa-hNFmBUz1ausV87ZacBpzu23u5r6cbN1CUbcHTY2G4dMXRgxxDxMPXRKj91mdfBhghjxHcehmzrgo12p3ELMmpv4SM6M9AHffl6ztHjj-8Ptz-z1e-7-9vFKpOcs5hRRQyIvAauJKm0KWjbGp7L0sjW5LUgldAVb7lihNSi4BVtdQ6E5TK1aEv5HH0-zE3_e5p0iM1gg9R9D6N2U2hYxeoybSVtco4-vaMbN_kxvS6pkuaFKLlI6stBSe9C8No0W28H8H8bSpp_eTRLvnzY57FI-OZ15NQOWh3pWwAJXB-AD_LY_R8ofwE-mZET</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2871564734</pqid></control><display><type>article</type><title>Novel valproate half-sandwich rhodium and iridium conjugates to fight against multidrug-resistant Gram-positive bacteria</title><source>Royal Society Of Chemistry Journals</source><source>Alma/SFX Local Collection</source><creator>Marco, Alicia ; Vigueras, Gloria ; Busto, Natalia ; Cutillas, Natalia ; Bautista, Delia ; Ruiz, José</creator><creatorcontrib>Marco, Alicia ; Vigueras, Gloria ; Busto, Natalia ; Cutillas, Natalia ; Bautista, Delia ; Ruiz, José</creatorcontrib><description>New valproate Ir(
iii
) and Rh(
iii
) half-sandwich conjugates containing a C,N-phenylbenzimidazole chelated ligand have been synthesized and characterized. The valproic acid conjugation to organometallic fragments seems to switch on the antibacterial activity of the complexes towards
Enterococcus faecium
and
Staphylococcus aureus
Gram-positive bacteria.
The valproic acid conjugation to Ir(
iii
) and Rh(
iii
) half-sandwich complexes seems to switch on their antibacterial activity towards
Enterococcus faecium
and
Staphylococcus aureus
Gram-positive bacteria.</description><identifier>ISSN: 1477-9226</identifier><identifier>EISSN: 1477-9234</identifier><identifier>DOI: 10.1039/d3dt01678a</identifier><identifier>PMID: 37358044</identifier><language>eng</language><publisher>England: Royal Society of Chemistry</publisher><subject>Bacteria ; Conjugates ; Conjugation ; Iridium ; Rhodium</subject><ispartof>Dalton transactions : an international journal of inorganic chemistry, 2023-10, Vol.52 (38), p.13482-13486</ispartof><rights>Copyright Royal Society of Chemistry 2023</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c332t-1d0fa459a3dc08ef61bbf35c7fcbf594084e83b3d200946381be5a025c4081b13</cites><orcidid>0000-0001-9637-1209 ; 0000-0002-0834-337X ; 0000-0002-8449-6968 ; 0000-0002-6711-8076</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37358044$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Marco, Alicia</creatorcontrib><creatorcontrib>Vigueras, Gloria</creatorcontrib><creatorcontrib>Busto, Natalia</creatorcontrib><creatorcontrib>Cutillas, Natalia</creatorcontrib><creatorcontrib>Bautista, Delia</creatorcontrib><creatorcontrib>Ruiz, José</creatorcontrib><title>Novel valproate half-sandwich rhodium and iridium conjugates to fight against multidrug-resistant Gram-positive bacteria</title><title>Dalton transactions : an international journal of inorganic chemistry</title><addtitle>Dalton Trans</addtitle><description>New valproate Ir(
iii
) and Rh(
iii
) half-sandwich conjugates containing a C,N-phenylbenzimidazole chelated ligand have been synthesized and characterized. The valproic acid conjugation to organometallic fragments seems to switch on the antibacterial activity of the complexes towards
Enterococcus faecium
and
Staphylococcus aureus
Gram-positive bacteria.
The valproic acid conjugation to Ir(
iii
) and Rh(
iii
) half-sandwich complexes seems to switch on their antibacterial activity towards
Enterococcus faecium
and
Staphylococcus aureus
Gram-positive bacteria.</description><subject>Bacteria</subject><subject>Conjugates</subject><subject>Conjugation</subject><subject>Iridium</subject><subject>Rhodium</subject><issn>1477-9226</issn><issn>1477-9234</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNpd0ctrGzEQB2AREuLUzSX3BEEvpbCtXvs6mrhNA6a9JOdlVo-1zO7KkbRO-99HtRMXctKI-Rik-SF0RclXSnj9TXEVCS3KCk7QBRVlmdWMi9NjzYoZ-hDChhDGSM7O0YyXPK-IEBfozy-30z3eQb_1DqLGa-hNFmBUz1ausV87ZacBpzu23u5r6cbN1CUbcHTY2G4dMXRgxxDxMPXRKj91mdfBhghjxHcehmzrgo12p3ELMmpv4SM6M9AHffl6ztHjj-8Ptz-z1e-7-9vFKpOcs5hRRQyIvAauJKm0KWjbGp7L0sjW5LUgldAVb7lihNSi4BVtdQ6E5TK1aEv5HH0-zE3_e5p0iM1gg9R9D6N2U2hYxeoybSVtco4-vaMbN_kxvS6pkuaFKLlI6stBSe9C8No0W28H8H8bSpp_eTRLvnzY57FI-OZ15NQOWh3pWwAJXB-AD_LY_R8ofwE-mZET</recordid><startdate>20231003</startdate><enddate>20231003</enddate><creator>Marco, Alicia</creator><creator>Vigueras, Gloria</creator><creator>Busto, Natalia</creator><creator>Cutillas, Natalia</creator><creator>Bautista, Delia</creator><creator>Ruiz, José</creator><general>Royal Society of Chemistry</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>L7M</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-9637-1209</orcidid><orcidid>https://orcid.org/0000-0002-0834-337X</orcidid><orcidid>https://orcid.org/0000-0002-8449-6968</orcidid><orcidid>https://orcid.org/0000-0002-6711-8076</orcidid></search><sort><creationdate>20231003</creationdate><title>Novel valproate half-sandwich rhodium and iridium conjugates to fight against multidrug-resistant Gram-positive bacteria</title><author>Marco, Alicia ; Vigueras, Gloria ; Busto, Natalia ; Cutillas, Natalia ; Bautista, Delia ; Ruiz, José</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c332t-1d0fa459a3dc08ef61bbf35c7fcbf594084e83b3d200946381be5a025c4081b13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Bacteria</topic><topic>Conjugates</topic><topic>Conjugation</topic><topic>Iridium</topic><topic>Rhodium</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Marco, Alicia</creatorcontrib><creatorcontrib>Vigueras, Gloria</creatorcontrib><creatorcontrib>Busto, Natalia</creatorcontrib><creatorcontrib>Cutillas, Natalia</creatorcontrib><creatorcontrib>Bautista, Delia</creatorcontrib><creatorcontrib>Ruiz, José</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><jtitle>Dalton transactions : an international journal of inorganic chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Marco, Alicia</au><au>Vigueras, Gloria</au><au>Busto, Natalia</au><au>Cutillas, Natalia</au><au>Bautista, Delia</au><au>Ruiz, José</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Novel valproate half-sandwich rhodium and iridium conjugates to fight against multidrug-resistant Gram-positive bacteria</atitle><jtitle>Dalton transactions : an international journal of inorganic chemistry</jtitle><addtitle>Dalton Trans</addtitle><date>2023-10-03</date><risdate>2023</risdate><volume>52</volume><issue>38</issue><spage>13482</spage><epage>13486</epage><pages>13482-13486</pages><issn>1477-9226</issn><eissn>1477-9234</eissn><abstract>New valproate Ir(
iii
) and Rh(
iii
) half-sandwich conjugates containing a C,N-phenylbenzimidazole chelated ligand have been synthesized and characterized. The valproic acid conjugation to organometallic fragments seems to switch on the antibacterial activity of the complexes towards
Enterococcus faecium
and
Staphylococcus aureus
Gram-positive bacteria.
The valproic acid conjugation to Ir(
iii
) and Rh(
iii
) half-sandwich complexes seems to switch on their antibacterial activity towards
Enterococcus faecium
and
Staphylococcus aureus
Gram-positive bacteria.</abstract><cop>England</cop><pub>Royal Society of Chemistry</pub><pmid>37358044</pmid><doi>10.1039/d3dt01678a</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0001-9637-1209</orcidid><orcidid>https://orcid.org/0000-0002-0834-337X</orcidid><orcidid>https://orcid.org/0000-0002-8449-6968</orcidid><orcidid>https://orcid.org/0000-0002-6711-8076</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1477-9226 |
| ispartof | Dalton transactions : an international journal of inorganic chemistry, 2023-10, Vol.52 (38), p.13482-13486 |
| issn | 1477-9226 1477-9234 |
| language | eng |
| recordid | cdi_proquest_journals_2871564734 |
| source | Royal Society Of Chemistry Journals; Alma/SFX Local Collection |
| subjects | Bacteria Conjugates Conjugation Iridium Rhodium |
| title | Novel valproate half-sandwich rhodium and iridium conjugates to fight against multidrug-resistant Gram-positive bacteria |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-20T06%3A31%3A36IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Novel%20valproate%20half-sandwich%20rhodium%20and%20iridium%20conjugates%20to%20fight%20against%20multidrug-resistant%20Gram-positive%20bacteria&rft.jtitle=Dalton%20transactions%20:%20an%20international%20journal%20of%20inorganic%20chemistry&rft.au=Marco,%20Alicia&rft.date=2023-10-03&rft.volume=52&rft.issue=38&rft.spage=13482&rft.epage=13486&rft.pages=13482-13486&rft.issn=1477-9226&rft.eissn=1477-9234&rft_id=info:doi/10.1039/d3dt01678a&rft_dat=%3Cproquest_cross%3E2871564734%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2871564734&rft_id=info:pmid/37358044&rfr_iscdi=true |