Prognostic potential and pathological validation of a diagnostic application using Raman spectroscopy in the characterization of degenerative changes in the cartilage of the humeral head

Raman spectroscopy is a well-established analytical method in the fields of chemistry, industry, biology, pharmaceutics, and medicine. Previous studies have investigated optical imaging and Raman spectroscopy for osteoarthritis (OA) diagnosis in weight-bearing joints such as hip and knee joints. How...

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Veröffentlicht in:	Journal of biomedical optics 2022-11, Vol.27 (11), p.115002-115002
Hauptverfasser:	Asaoka, Ryuji, Kiyomatsu, Hiroshi, Miura, Hiromasa, Jono, Akihiro, Kinoshita, Tomofumi, Takao, Masaki, Katagiri, Takashi, Oshima, Yusuke
Format:	Artikel
Sprache:	eng
Schlagworte:	Cartilage Cartilage diseases Cartilage, Articular - chemistry Cluster analysis Collagen Collagen - analysis Correlation Diagnosis Glycosaminoglycans Glycosaminoglycans - analysis Hip Humans Humeral Head - chemistry Humeral Head - pathology Humerus Hydroxyapatite Joints (anatomy) Lasers Machine learning Mathematical analysis Microscopy Multivariate analysis Osteoarthritis Osteoarthritis - diagnostic imaging Osteoarthritis - pathology Principal components analysis Prognosis Proteins Proteoglycans Raman spectroscopy Shoulder Spectroscopy Spectrum analysis Spectrum Analysis, Raman - methods Staining Unsupervised learning X-rays
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