A commentary on the inhibition of human TPC2 channel by the natural flavonoid naringenin: Methods, experiments, and ideas

Human endo-lysosomes possess a class of proteins called TPC channels on their membrane, which are essential for proper cell functioning. This protein family can be functionally studied by expressing them in plant vacuoles. Inhibition of hTPC activity by naringenin, one of the main flavonoids present...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biomolecular Concepts 2023-09, Vol.14 (1), p.1143-55
Hauptverfasser:	Minicozzi, Velia, Qi, Tianwen, Gradogna, Antonella, Pozzolini, Marina, Milenkovic, Stefan, Filippini, Antonio, Ceccarelli, Matteo, Carpaneto, Armando
Format:	Artikel
Sprache:	eng
Schlagworte:	Flavonoids Lysosomes Melanoma Naringenin patch-clamp plant vacuole Solid tumors tpc channels Vacuoles
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!