Thulium-Doped Fiber Laser and Its Application in Urinary Lithotripsy
Purpose Thulium-doped fiber laser (TFL)-based urological lithotripsy has emerged as a promising technology for treating urological stones in new era of endourological options. The objective of this review is to provide a comprehensive summary of the characteristics of TFL application for lithotripsy...
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| Veröffentlicht in: | Journal of medical and biological engineering 2023-08, Vol.43 (4), p.351-361 |
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| creator | Gu, Runyan Li, Zhilong Lei, Cheng Li, Sheng Wang, Du Wang, Xinghuan |
| description | Purpose
Thulium-doped fiber laser (TFL)-based urological lithotripsy has emerged as a promising technology for treating urological stones in new era of endourological options. The objective of this review is to provide a comprehensive summary of the characteristics of TFL application for lithotripsy and to analyze the research progress of two crucial TFL light sources, quasi-continuous (QCW) TFL and main oscillation power amplification (MOPA) TFL.
Methods
The data about the potential efficiency of TFL in clinical applications and the status of pulsed TFL studies were gathered through a manual search of TFL-related literature in the SCI, SSCI, A&HCI, IE, PubMed databases to assess the performance issues associated with application of thulium laser for urinary tract stone surgery.
Results
TFLs can ablate stones mainly through photothermal and micro-explosive effects. In clinical trials, thulium laser has been established to be superior to holmium laser in terms of lithotripsy efficiency, tissue damage, lithotripsy retreating effect, thermal effect, intraoperative visualization, and postoperative lithotripsy-free rate, which is more widely used currently. Among the various pulsed TFLs, QCW TFL provides flexible beam waveform, high electro-optical conversion efficiency, high heat dissipation performance, and low material maintenance requirements. MOPA TFL can flexibly affect the morphology of the output pulse within a wide range while significantly increasing the output power.
Conclusion
TFL represents a safer, more effective and comprehensive tool for the treatment of urinary stone. Although QCW TFL is currently the mainstream laser source for lithotripsy, we anticipate that MOPA technology has the potential to offer number of advantages while it has not yet received sufficient attention. Further studies are still needed to optimize the performance of pulsed TFLs to facilitate the development of thulium laser lithotripsy. |
| doi_str_mv | 10.1007/s40846-023-00813-z |
| format | Article |
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Thulium-doped fiber laser (TFL)-based urological lithotripsy has emerged as a promising technology for treating urological stones in new era of endourological options. The objective of this review is to provide a comprehensive summary of the characteristics of TFL application for lithotripsy and to analyze the research progress of two crucial TFL light sources, quasi-continuous (QCW) TFL and main oscillation power amplification (MOPA) TFL.
Methods
The data about the potential efficiency of TFL in clinical applications and the status of pulsed TFL studies were gathered through a manual search of TFL-related literature in the SCI, SSCI, A&HCI, IE, PubMed databases to assess the performance issues associated with application of thulium laser for urinary tract stone surgery.
Results
TFLs can ablate stones mainly through photothermal and micro-explosive effects. In clinical trials, thulium laser has been established to be superior to holmium laser in terms of lithotripsy efficiency, tissue damage, lithotripsy retreating effect, thermal effect, intraoperative visualization, and postoperative lithotripsy-free rate, which is more widely used currently. Among the various pulsed TFLs, QCW TFL provides flexible beam waveform, high electro-optical conversion efficiency, high heat dissipation performance, and low material maintenance requirements. MOPA TFL can flexibly affect the morphology of the output pulse within a wide range while significantly increasing the output power.
Conclusion
TFL represents a safer, more effective and comprehensive tool for the treatment of urinary stone. Although QCW TFL is currently the mainstream laser source for lithotripsy, we anticipate that MOPA technology has the potential to offer number of advantages while it has not yet received sufficient attention. Further studies are still needed to optimize the performance of pulsed TFLs to facilitate the development of thulium laser lithotripsy.</description><identifier>ISSN: 1609-0985</identifier><identifier>EISSN: 2199-4757</identifier><identifier>DOI: 10.1007/s40846-023-00813-z</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Ablation ; Beams (structural) ; Biological Techniques ; Biomedical and Life Sciences ; Biomedical Engineering and Bioengineering ; Biomedical Engineering/Biotechnology ; Biomedicine ; Clinical trials ; Doped fibers ; Efficiency ; Fiber lasers ; Holmium ; Lasers ; Light sources ; Lithotripsy ; Photothermal conversion ; Regenerative Medicine/Tissue Engineering ; Review Article ; Stone ; Temperature effects ; Thulium ; Urinary tract ; Waveforms</subject><ispartof>Journal of medical and biological engineering, 2023-08, Vol.43 (4), p.351-361</ispartof><rights>Taiwanese Society of Biomedical Engineering 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c319t-3a0c540838f75964a31af6985e730af78b1e4b0012578332d3e9087f1fde98283</citedby><cites>FETCH-LOGICAL-c319t-3a0c540838f75964a31af6985e730af78b1e4b0012578332d3e9087f1fde98283</cites><orcidid>0000-0002-0098-7613</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s40846-023-00813-z$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s40846-023-00813-z$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids></links><search><creatorcontrib>Gu, Runyan</creatorcontrib><creatorcontrib>Li, Zhilong</creatorcontrib><creatorcontrib>Lei, Cheng</creatorcontrib><creatorcontrib>Li, Sheng</creatorcontrib><creatorcontrib>Wang, Du</creatorcontrib><creatorcontrib>Wang, Xinghuan</creatorcontrib><title>Thulium-Doped Fiber Laser and Its Application in Urinary Lithotripsy</title><title>Journal of medical and biological engineering</title><addtitle>J. Med. Biol. Eng</addtitle><description>Purpose
Thulium-doped fiber laser (TFL)-based urological lithotripsy has emerged as a promising technology for treating urological stones in new era of endourological options. The objective of this review is to provide a comprehensive summary of the characteristics of TFL application for lithotripsy and to analyze the research progress of two crucial TFL light sources, quasi-continuous (QCW) TFL and main oscillation power amplification (MOPA) TFL.
Methods
The data about the potential efficiency of TFL in clinical applications and the status of pulsed TFL studies were gathered through a manual search of TFL-related literature in the SCI, SSCI, A&HCI, IE, PubMed databases to assess the performance issues associated with application of thulium laser for urinary tract stone surgery.
Results
TFLs can ablate stones mainly through photothermal and micro-explosive effects. In clinical trials, thulium laser has been established to be superior to holmium laser in terms of lithotripsy efficiency, tissue damage, lithotripsy retreating effect, thermal effect, intraoperative visualization, and postoperative lithotripsy-free rate, which is more widely used currently. Among the various pulsed TFLs, QCW TFL provides flexible beam waveform, high electro-optical conversion efficiency, high heat dissipation performance, and low material maintenance requirements. MOPA TFL can flexibly affect the morphology of the output pulse within a wide range while significantly increasing the output power.
Conclusion
TFL represents a safer, more effective and comprehensive tool for the treatment of urinary stone. Although QCW TFL is currently the mainstream laser source for lithotripsy, we anticipate that MOPA technology has the potential to offer number of advantages while it has not yet received sufficient attention. Further studies are still needed to optimize the performance of pulsed TFLs to facilitate the development of thulium laser lithotripsy.</description><subject>Ablation</subject><subject>Beams (structural)</subject><subject>Biological Techniques</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedical Engineering and Bioengineering</subject><subject>Biomedical Engineering/Biotechnology</subject><subject>Biomedicine</subject><subject>Clinical trials</subject><subject>Doped fibers</subject><subject>Efficiency</subject><subject>Fiber lasers</subject><subject>Holmium</subject><subject>Lasers</subject><subject>Light sources</subject><subject>Lithotripsy</subject><subject>Photothermal conversion</subject><subject>Regenerative Medicine/Tissue Engineering</subject><subject>Review Article</subject><subject>Stone</subject><subject>Temperature effects</subject><subject>Thulium</subject><subject>Urinary tract</subject><subject>Waveforms</subject><issn>1609-0985</issn><issn>2199-4757</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNp9kDFPwzAQhS0EElXpH2CKxGw4-5LYHquW0kqRWNrZchOHumqTYCdD--sxBImNG-6W9949fYQ8MnhmAOIlpCDTnAJHCiAZ0usNmXCmFE1FJm7JhOWgKCiZ3ZNZCEeIgyrPmZyQ5fYwnNxwpsu2s1Wycnvrk8KEuE1TJZs-JPOuO7nS9K5tEtckO-8a4y9J4fpD23vXhcsDuavNKdjZ752S3ep1u1jT4v1ts5gXtESmeooGyix2RVmLTOWpQWbqPNayAsHUQu6ZTfcAjGdCIvIKrQIpalZXVkkucUqextzOt5-DDb0-toNv4kvNZUzMEBGiio-q0rcheFvrzrtzrKwZ6G9gegSmIzD9A0xfowlHU4ji5sP6v-h_XF__i2x6</recordid><startdate>20230801</startdate><enddate>20230801</enddate><creator>Gu, Runyan</creator><creator>Li, Zhilong</creator><creator>Lei, Cheng</creator><creator>Li, Sheng</creator><creator>Wang, Du</creator><creator>Wang, Xinghuan</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><orcidid>https://orcid.org/0000-0002-0098-7613</orcidid></search><sort><creationdate>20230801</creationdate><title>Thulium-Doped Fiber Laser and Its Application in Urinary Lithotripsy</title><author>Gu, Runyan ; Li, Zhilong ; Lei, Cheng ; Li, Sheng ; Wang, Du ; Wang, Xinghuan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c319t-3a0c540838f75964a31af6985e730af78b1e4b0012578332d3e9087f1fde98283</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Ablation</topic><topic>Beams (structural)</topic><topic>Biological Techniques</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedical Engineering and Bioengineering</topic><topic>Biomedical Engineering/Biotechnology</topic><topic>Biomedicine</topic><topic>Clinical trials</topic><topic>Doped fibers</topic><topic>Efficiency</topic><topic>Fiber lasers</topic><topic>Holmium</topic><topic>Lasers</topic><topic>Light sources</topic><topic>Lithotripsy</topic><topic>Photothermal conversion</topic><topic>Regenerative Medicine/Tissue Engineering</topic><topic>Review Article</topic><topic>Stone</topic><topic>Temperature effects</topic><topic>Thulium</topic><topic>Urinary tract</topic><topic>Waveforms</topic><toplevel>online_resources</toplevel><creatorcontrib>Gu, Runyan</creatorcontrib><creatorcontrib>Li, Zhilong</creatorcontrib><creatorcontrib>Lei, Cheng</creatorcontrib><creatorcontrib>Li, Sheng</creatorcontrib><creatorcontrib>Wang, Du</creatorcontrib><creatorcontrib>Wang, Xinghuan</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><jtitle>Journal of medical and biological engineering</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gu, Runyan</au><au>Li, Zhilong</au><au>Lei, Cheng</au><au>Li, Sheng</au><au>Wang, Du</au><au>Wang, Xinghuan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Thulium-Doped Fiber Laser and Its Application in Urinary Lithotripsy</atitle><jtitle>Journal of medical and biological engineering</jtitle><stitle>J. Med. Biol. Eng</stitle><date>2023-08-01</date><risdate>2023</risdate><volume>43</volume><issue>4</issue><spage>351</spage><epage>361</epage><pages>351-361</pages><issn>1609-0985</issn><eissn>2199-4757</eissn><abstract>Purpose
Thulium-doped fiber laser (TFL)-based urological lithotripsy has emerged as a promising technology for treating urological stones in new era of endourological options. The objective of this review is to provide a comprehensive summary of the characteristics of TFL application for lithotripsy and to analyze the research progress of two crucial TFL light sources, quasi-continuous (QCW) TFL and main oscillation power amplification (MOPA) TFL.
Methods
The data about the potential efficiency of TFL in clinical applications and the status of pulsed TFL studies were gathered through a manual search of TFL-related literature in the SCI, SSCI, A&HCI, IE, PubMed databases to assess the performance issues associated with application of thulium laser for urinary tract stone surgery.
Results
TFLs can ablate stones mainly through photothermal and micro-explosive effects. In clinical trials, thulium laser has been established to be superior to holmium laser in terms of lithotripsy efficiency, tissue damage, lithotripsy retreating effect, thermal effect, intraoperative visualization, and postoperative lithotripsy-free rate, which is more widely used currently. Among the various pulsed TFLs, QCW TFL provides flexible beam waveform, high electro-optical conversion efficiency, high heat dissipation performance, and low material maintenance requirements. MOPA TFL can flexibly affect the morphology of the output pulse within a wide range while significantly increasing the output power.
Conclusion
TFL represents a safer, more effective and comprehensive tool for the treatment of urinary stone. Although QCW TFL is currently the mainstream laser source for lithotripsy, we anticipate that MOPA technology has the potential to offer number of advantages while it has not yet received sufficient attention. Further studies are still needed to optimize the performance of pulsed TFLs to facilitate the development of thulium laser lithotripsy.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><doi>10.1007/s40846-023-00813-z</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0002-0098-7613</orcidid></addata></record> |
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| subjects | Ablation Beams (structural) Biological Techniques Biomedical and Life Sciences Biomedical Engineering and Bioengineering Biomedical Engineering/Biotechnology Biomedicine Clinical trials Doped fibers Efficiency Fiber lasers Holmium Lasers Light sources Lithotripsy Photothermal conversion Regenerative Medicine/Tissue Engineering Review Article Stone Temperature effects Thulium Urinary tract Waveforms |
| title | Thulium-Doped Fiber Laser and Its Application in Urinary Lithotripsy |
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