Royal jelly controls intestinal stem cell homeostasis via SIRT1/mTORC1 axis

Background and objectives: The homeostasis of the gut epithelium is maintained by the self-renewal and differentiation of intestinal stem cells (ISCs). As previous studies have described the aging-related deterioration of adult stem cell function, developing the interventions to increase the adult s...

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Veröffentlicht in:	Annals of nutrition and metabolism 2023-08, Vol.79, p.523
Hauptverfasser:	Igarashi, Masaki, Miura, Masaomi, Isotani, Ryosuke, Nakagawa, Yoshiko, Naruse, Kyoko, Okumura, Nobuaki, Yamauchi, Toshimasa
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Cell activation Cell culture Cell differentiation Cell proliferation Cell self-renewal Cells Crypts Epithelium Homeostasis Immunohistochemistry Inhibitors Intestine Medical treatment mRNA Nutrient deficiency Organoids Paneth cells Rodents Royal jelly SIRT1 protein Small intestine Stem cells STEM education
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