The role of intestinal Cytochrome P450 in vitamin D metabolism

Background and objectives: Physiological vitamin D status is important for bone health. Vitamin D hydroxylation in the liver/kidney results in conversion to its physiologically active form of "1,25-dihydroxyvitamin D" (1,25D). 1,25D controls gene expression through the nuclear vitamin D re...

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Veröffentlicht in:	Annals of nutrition and metabolism 2023-08, Vol.79, p.670
Hauptverfasser:	Uga, Minori, Kaneko, Ichiro, Sasaki, Sumire, Koike, Megumi, Tanifuji, Kazuya, Kawahara, Kota, Shiozaki, Yuji, Jurutka, Peter W, Segawa, Hiroko
Format:	Artikel
Sprache:	eng
Schlagworte:	25-Hydroxyvitamin D Amino acids Calciferol Calcium absorption Calcium channels Calcium ions Carbamazepine Cytochrome Cytochrome P450 Cytochromes P450 Epilepsy Gene expression Homeostasis Homology Hydroxylation Inactivation Intestine Kidneys Liver Liver diseases Osteoporosis Phenobarbital Phenytoin Physiology Pioglitazone Plasmids Polymerase chain reaction Real time Receptors Retinoid X receptors Rickets Substrates Transient receptor potential proteins Vitamin A Vitamin D Vitamin D receptors Vitamin deficiency Vitamins Western blotting
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