Effects of Asian-based oil blends made from refined rice bran, flaxseed and sesame seed oils on lipoprotein particle size distribution

Background and objective: Low density lipoprotein (LDL) cholesterol particle size distribution have implications on atherosclerosis risk. As part of a dietary intervention trial where volunteers consumed either one of two vegetable oil blends made with different proportions of refined rice bran, flaxseed and sesame seed oils, or refined olive oil (control), the objective of this study was to determine the effects of consuming these oils on the distribution of the LDL subfractions. Methods: This secondary analysis was undertaken using serum samples collected as part of the 8-week, three-arm, parallel design, randomised controlled trial in 135 borderline hypercholesterolemic older Chinese adults. LDL subfractions analysis were conducted using the Lipoprint LDL system. Results: There were significant reductions in intermediate density lipoprotein (IDL) cholesterol concentration in all three intervention groups over time (-6.07%;