A controllable perfusion microfluidic chip for facilitating the development of retinal ganglion cells in human retinal organoids

Retinal organoids (ROs) derived from human pluripotent stem cells (hPSCs) have become a promising model in vitro to recapitulate human retinal development, which can be further employed to explore the mechanisms of retinal diseases. However, the current culture systems for ROs lack physiologically r...

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Veröffentlicht in:	Lab on a chip 2023-08, Vol.23 (17), p.382-3836
Hauptverfasser:	Gong, Jing, Gong, Yu, Zou, Ting, Zeng, Yuxiao, Yang, Cao, Mo, Lingyue, Kang, Jiahui, Fan, Xiaotang, Xu, Haiwei, Yang, Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Controllability Culture Gene sequencing Ion channels Ions Microfluidics Shear stress Stem cells Transplantation
Online-Zugang:	Volltext
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