857-P: Quiescence Recovers Adipose Tissue–Derived Stromal Cells from Senescence-Associated Secretory Phenotype, Leading to Enhanced Angiogenesis and Diabetic Wound Healing

Although a number of studies have shown that mesenchymal stem cells (MSCs) promote diabetic wound healing, their clinical applications are still limited. One of the reasons is that MSCs exhibit a senescence-associated secretory phenotype (SASP) in diabetes, which results in attenuation of their anti...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2023-06, Vol.72 (Supplement_1), p.1
Hauptverfasser:	FUNAKI, MAKOTO, HATA, AKIKO, YOSHIDA, MITSUTERU, MIYAMOTO, NAOKI, IKUTA, TAKAHISA, UEMURA, YUTA, AKIZUKI, MINATO, TANGOKU, AKIRA, YUMOTO, HIROMICHI, OGAWA, HIROHISA, OYA, TAKESHI
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissue Angiogenesis Body fat Clinical trials Diabetes Diabetes mellitus Endothelial cells Gels Glucose Inflammation Mesenchymal stem cells Phenotypes Senescence Stromal cells Wound healing
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