475-P: Intermittent Hypoxia Increased the Expression of Intercellular Adhesion Molecule-1 and Endothelial Cell–Specific Molecule-1 in Vascular Endothelial Cells via the Downregulation of MicroRNA-181a1

Sleep apnea syndrome (SAS), which is characterized by recurrent episodes of oxygen desaturation and reoxygenation (intermittent hypoxia [IH]), is a risk factor for vascular dysfunction, as well as hypertension, and insulin resistance/Type 2 diabetes. We have reported correlations between IH and insu...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2023-06, Vol.72 (Supplement_1), p.1
Hauptverfasser:	TAKASAWA, SHIN, MAKINO, MAI, YAMAUCHI, AKIYO, SAKURAMOTO-TSUCHIDA, SUMIYO, TAKEDA, YOSHINORI, UCHIYAMA, TOMOKO, SHOBATAKE, RYOGO
Format:	Artikel
Sprache:	eng
Schlagworte:	Apnea Arteriosclerosis Cell adhesion molecules Chemokines Diabetes Diabetes mellitus (non-insulin dependent) Endothelial cells Endothelin 1 Enzyme-linked immunosorbent assay Hypertension Hypoxia Inflammation Insulin resistance Intercellular adhesion molecule 1 MicroRNAs miRNA Nitric oxide Nitric-oxide synthase Risk factors Sleep disorders Vascular cell adhesion molecule 1
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