93-OR: Hepatic Acyl-Protein Thioesterases Prevent Insulin Resistance

Elevated fatty acids in the context of metabolic disease are associated with insulin resistance. Fatty acids covalently and reversibly modify proteins through a process known as palmitoylation. We hypothesized that depalmitoylation by acyl-protein thioesterases 1 and 2 (APT1 and APT2) in the liver r...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2023-06, Vol.72 (Supplement_1), p.1
Hauptverfasser:	SPECK, SARAH L., ZHANG, QIANG, BHATT, DHAVAL P., ADAK, SANGEETA, DONG, GUIFANG, WEI, XIAOCHAO, SEMENKOVICH, CLAY F.
Format:	Artikel
Sprache:	eng
Schlagworte:	AKT protein Amino acids Biotin Fatty acids Gluconeogenesis Glucose Glucose metabolism Glutamine Hepatocellular carcinoma High fat diet Insulin resistance Liver Mass spectrometry Mass spectroscopy Metabolic disorders Metabolism Mitochondria Palmitoylation Protein purification Proteins Scientific imaging Thioesterase
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!