1207-P: Gestational Diabetes Mellitus (GDM)—Outcomes for Normal-Weight Individuals

Excess body weight is associated with GDM, and BMI ≥ 25kg/m2 is often used as a criterion in risk factor-based screening programs. However, individuals with a normal BMI account for a significant proportion of those diagnosed with GDM (20-60% depending on the population studied), and comparative cli...

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Veröffentlicht in:Diabetes (New York, N.Y.) N.Y.), 2023-06, Vol.72 (Supplement_1), p.1
Hauptverfasser: MOAZZAMI, MITRA, VENKATESAN, NANDITHA, SANKARAN RAJAGOPALAN, KAMALNATH, VELLA, ADRIAN, EGAN, AOIFE M.
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container_issue Supplement_1
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container_title Diabetes (New York, N.Y.)
container_volume 72
creator MOAZZAMI, MITRA
VENKATESAN, NANDITHA
SANKARAN RAJAGOPALAN, KAMALNATH
VELLA, ADRIAN
EGAN, AOIFE M.
description Excess body weight is associated with GDM, and BMI ≥ 25kg/m2 is often used as a criterion in risk factor-based screening programs. However, individuals with a normal BMI account for a significant proportion of those diagnosed with GDM (20-60% depending on the population studied), and comparative clinical outcome data are limited. Our aim was to assess pregnancy outcomes for people with GDM and a baseline BMI < 25kg/m2, compared to a reference group with GDM and a BMI of 25-30kg/m2. Included subjects attended our institution for prenatal care from 2018-22 and GDM was diagnosed using universal screening and Carpenter and Coustan criteria. We identified 524 individuals with a BMI < 25kg/m2 and 705 with a BMI 25-30kg/m2. Those with a BMI
doi_str_mv 10.2337/db23-1207-P
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However, individuals with a normal BMI account for a significant proportion of those diagnosed with GDM (20-60% depending on the population studied), and comparative clinical outcome data are limited. Our aim was to assess pregnancy outcomes for people with GDM and a baseline BMI < 25kg/m2, compared to a reference group with GDM and a BMI of 25-30kg/m2. Included subjects attended our institution for prenatal care from 2018-22 and GDM was diagnosed using universal screening and Carpenter and Coustan criteria. We identified 524 individuals with a BMI < 25kg/m2 and 705 with a BMI 25-30kg/m2. Those with a BMI <25 kg/m2 were younger (22 v 28 years, p<0.001), and a higher proportion identified as Asian (15.5% v 9.22%; p=0.04). Table 1 contains pregnancy outcomes. Those with a BMI <25kg/m2 were less likely to receive pharmacological GDM therapy, but their infants had a higher rate of neonatal ICU admission. Postpartum, those with a BMI <25kg/m2 were less likely to have an oral glucose tolerance test but were at similar risk of glucose intolerance. These findings suggest that normal weight women with GDM may experience higher risk of adverse outcomes compared to their overweight counterparts. These data support universal screening and will be used to inform patients on their risk profile and improve postpartum screening.]]></description><identifier>ISSN: 0012-1797</identifier><identifier>EISSN: 1939-327X</identifier><identifier>DOI: 10.2337/db23-1207-P</identifier><language>eng</language><publisher>New York: American Diabetes Association</publisher><subject>Body weight ; Diabetes mellitus ; Gestational diabetes ; Glucose tolerance ; Intolerance ; Neonates ; Overweight ; Population studies ; Postpartum ; Pregnancy complications ; Risk factors</subject><ispartof>Diabetes (New York, N.Y.), 2023-06, Vol.72 (Supplement_1), p.1</ispartof><rights>Copyright American Diabetes Association Jun 2023</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids></links><search><creatorcontrib>MOAZZAMI, MITRA</creatorcontrib><creatorcontrib>VENKATESAN, NANDITHA</creatorcontrib><creatorcontrib>SANKARAN RAJAGOPALAN, KAMALNATH</creatorcontrib><creatorcontrib>VELLA, ADRIAN</creatorcontrib><creatorcontrib>EGAN, AOIFE M.</creatorcontrib><title>1207-P: Gestational Diabetes Mellitus (GDM)—Outcomes for Normal-Weight Individuals</title><title>Diabetes (New York, N.Y.)</title><description><![CDATA[Excess body weight is associated with GDM, and BMI ≥ 25kg/m2 is often used as a criterion in risk factor-based screening programs. However, individuals with a normal BMI account for a significant proportion of those diagnosed with GDM (20-60% depending on the population studied), and comparative clinical outcome data are limited. Our aim was to assess pregnancy outcomes for people with GDM and a baseline BMI < 25kg/m2, compared to a reference group with GDM and a BMI of 25-30kg/m2. Included subjects attended our institution for prenatal care from 2018-22 and GDM was diagnosed using universal screening and Carpenter and Coustan criteria. We identified 524 individuals with a BMI < 25kg/m2 and 705 with a BMI 25-30kg/m2. Those with a BMI <25 kg/m2 were younger (22 v 28 years, p<0.001), and a higher proportion identified as Asian (15.5% v 9.22%; p=0.04). Table 1 contains pregnancy outcomes. Those with a BMI <25kg/m2 were less likely to receive pharmacological GDM therapy, but their infants had a higher rate of neonatal ICU admission. 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Postpartum, those with a BMI <25kg/m2 were less likely to have an oral glucose tolerance test but were at similar risk of glucose intolerance. These findings suggest that normal weight women with GDM may experience higher risk of adverse outcomes compared to their overweight counterparts. These data support universal screening and will be used to inform patients on their risk profile and improve postpartum screening.]]></abstract><cop>New York</cop><pub>American Diabetes Association</pub><doi>10.2337/db23-1207-P</doi></addata></record>
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source EZB-FREE-00999 freely available EZB journals; PubMed Central
subjects Body weight
Diabetes mellitus
Gestational diabetes
Glucose tolerance
Intolerance
Neonates
Overweight
Population studies
Postpartum
Pregnancy complications
Risk factors
title 1207-P: Gestational Diabetes Mellitus (GDM)—Outcomes for Normal-Weight Individuals
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